AIMC Topic: Pharmaceutical Solutions
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Physicochemical stability of nefopam and nefopam/droperidol solutions in polypropylene syringes for intensive care units.
European journal of hospital pharmacy : science and practice
Jun 11, 2019
INTRODUCTION: Nefopam has been reported to be effective in postoperative pain control with an opioid-sparing effect, but the use of nefopam can lead to nausea and vomiting. To prevent these side effects, droperidol can be mixed with nefopam. In inten...
Assessment of the stability of citrate-buffered flucloxacillin for injection when stored in two commercially available ambulatory elastomeric devices: INfusor LV (Baxter) and Accufuser (Woo Young Medical): a study compliant with the NHS Yellow Cover Document (YCD) requirements.
European journal of hospital pharmacy : science and practice
Sep 18, 2018
OBJECTIVES: To investigate the effect of pH and buffers on the degradation rate of flucloxacillin and to determine if flucloxacillin can be stabilised using a buffered diluent for up to 14 days when stored at 2°C-8°C including a 24-hour infusion peri...
Physicochemical stability of etoposide diluted at range concentrations between 0.38 and 1.75 mg/mL in polyolefin bags.
European journal of hospital pharmacy : science and practice
Jul 7, 2018
INTRODUCTION: According to the manufacturers, the diluted solution of etoposide should not exceed 0.4 mg/mL because precipitation may occur. For high doses or for patients requiring fluid restrictions, etoposide phosphate may be an option but shortag...
Stability of infliximab solutions in different temperature and dilution conditions.
Journal of pharmaceutical and biomedical analysis
Dec 18, 2017
Infliximab is a monoclonal antibody widely used for the treatment of inflammatory diseases. Over the past few years, many studies have assessed that monoclonal antibodies are prone to aggregation under stress conditions. The aim of this study was to ...
Chromatography, Ion Exchange
Nephelometry and Turbidimetry
Peptide Mapping
Protein Aggregates
Spectrophotometry, Ultraviolet
Chromatography, Gel
Drug Stability
Drug Compounding
Osmolar Concentration
Pharmaceutical Solutions
Technology, Pharmaceutical
Antirheumatic Agents
Infliximab
Biosimilar Pharmaceuticals
Protein Stability
Time Factors
Nanoparticles
Spectroscopy, Fourier Transform Infrared
Temperature
Media-fill simulation tests in manual and robotic aseptic preparation of injection solutions in syringes.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
Dec 30, 2014
OBJECTIVE: The purpose of this study was to evaluate the contamination rate of media-fill products either prepared automated with a robotic system (APOTECAchemo™) or prepared manually at cytotoxic workbenches in the same cleanroom environment and by ...
Caspofungin infusion solutions (50 mg/100 mL): chemical stability and antifungal activity against Candida spp.
Die Pharmazie
Apr 1, 2017
BACKGROUND: Ready to use caspofungin infusion bags are centrally prepared in the Hospital Pharmacy, University Hospital of Heidelberg, for economic reasons and possibly occurring problems with drug shortages. The aim of this study was a quality contr...
[The Influence of Different Ionic Concentration in Cell Physiological Solution on Temperature Measurement by Near Infrared].
Guang pu xue yu guang pu fen xi = Guang pu
Oct 1, 2015
It is important to real-timely monitor and control the temperature of cell physiological solution in patch clamp experiments, which can eliminate the uncertainty due to temperature and improve the measurement accuracy. This paper studies the influenc...
In-use Stability of Ceftaroline Fosamil in Elastomeric Home Infusion Systems and MINI-BAG Plus Containers.
International journal of pharmaceutical compounding
Jan 1, 2015
The objective of this study was to determine in-use stability of ceftaroline fosamil infusion solution of concentrations up to 12 mg/mL in elastomeric home infusion system prefilled with 0.9% Sodium Chloride Injection USP or 5% Dextrose Injection USP...
Stability of Levothyroxine, Doxycycline, Hydrocortisone, and Pravastatin in Liquid Dosage Forms Stored at Two Temperatures.
International journal of pharmaceutical compounding
Jan 1, 2015
Extemporaneously prepared liquid dosage forms are needed to administer required medications in infants and young children. The goal of this study was to evaluate the stability of levothyroxine, doxycycline, hydrocortisone, and pravastatin in extempor...
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