AIMC Topic: Positron-Emission Tomography

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Using domain knowledge for robust and generalizable deep learning-based CT-free PET attenuation and scatter correction.

Nature communications
Despite the potential of deep learning (DL)-based methods in substituting CT-based PET attenuation and scatter correction for CT-free PET imaging, a critical bottleneck is their limited capability in handling large heterogeneity of tracers and scanne...

Development of a deep learning network for Alzheimer's disease classification with evaluation of imaging modality and longitudinal data.

Physics in medicine and biology
. Neuroimaging uncovers important information about disease in the brain. Yet in Alzheimer's disease (AD), there remains a clear clinical need for reliable tools to extract diagnoses from neuroimages. Significant work has been done to develop deep le...

Breast PET/MRI Hybrid Imaging and Targeted Tracers.

Journal of magnetic resonance imaging : JMRI
The recent introduction of hybrid positron emission tomography/magnetic resonance imaging (PET/MRI) as a promising imaging modality for breast cancer assessment has prompted fervent research activity on its clinical applications. The current knowledg...

Deep Learning for Explainable Estimation of Mortality Risk From Myocardial Positron Emission Tomography Images.

Circulation. Cardiovascular imaging
BACKGROUND: We aim to develop an explainable deep learning (DL) network for the prediction of all-cause mortality directly from positron emission tomography myocardial perfusion imaging flow and perfusion polar map data and evaluate it using prospect...

Direct mapping from PET coincidence data to proton-dose and positron activity using a deep learning approach.

Physics in medicine and biology
. Obtaining the intrinsic dose distributions in particle therapy is a challenging problem that needs to be addressed by imaging algorithms to take advantage of secondary particle detectors. In this work, we investigate the utility of deep learning me...

Deep-TOF-PET: Deep learning-guided generation of time-of-flight from non-TOF brain PET images in the image and projection domains.

Human brain mapping
We aim to synthesize brain time-of-flight (TOF) PET images/sinograms from their corresponding non-TOF information in the image space (IS) and sinogram space (SS) to increase the signal-to-noise ratio (SNR) and contrast of abnormalities, and decrease ...

Mapping the association between tau-PET and Aβ-amyloid-PET using deep learning.

Scientific reports
In Alzheimer's disease, the molecular pathogenesis of the extracellular Aβ-amyloid (Aβ) instigation of intracellular tau accumulation is poorly understood. We employed a high-resolution PET scanner, with low detection thresholds, to examine the Aβ-ta...

Multimodal deep learning model on interim [F]FDG PET/CT for predicting primary treatment failure in diffuse large B-cell lymphoma.

European radiology
OBJECTIVES: The prediction of primary treatment failure (PTF) is necessary for patients with diffuse large B-cell lymphoma (DLBCL) since it serves as a prominent means for improving front-line outcomes. Using interim F-fluoro-2-deoxyglucose ([F]FDG) ...

Virtual high-count PET image generation using a deep learning method.

Medical physics
PURPOSE: Recently, deep learning-based methods have been established to denoise the low-count positron emission tomography (PET) images and predict their standard-count image counterparts, which could achieve reduction of injected dosage and scan tim...