AIMC Topic: Precision Medicine
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Can artificial intelligence accelerate preclinical drug discovery and precision medicine?
Expert opinion on drug discovery
Jun 19, 2022
Artificial intelligence and machine learning in precision and genomic medicine.
Medical oncology (Northwood, London, England)
Jun 15, 2022
The advancement of precision medicine in medical care has led behind the conventional symptom-driven treatment process by allowing early risk prediction of disease through improved diagnostics and customization of more effective treatments. It is nec...
Precision medicine using patient-specific modelling: state of the art and perspectives in dental practice.
Clinical oral investigations
Jun 10, 2022
The dental practice has largely evolved in the last 50 years following a better understanding of the biomechanical behaviour of teeth and its supporting structures, as well as developments in the fields of imaging and biomaterials. However, many pati...
Radiomics and artificial intelligence in malignant uterine body cancers: Protocol for a systematic review.
PloS one
Jun 8, 2022
INTRODUCTION: Uterine body cancers (UBC) are represented by endometrial carcinoma (EC) and uterine sarcoma (USa). The clinical management of both is hindered by the complex classification of patients into risk classes. This problem could be simplifie...
Combining Deep Learning and Radiomics for Automated, Objective, Comprehensive Bone Marrow Characterization From Whole-Body MRI: A Multicentric Feasibility Study.
Investigative radiology
May 27, 2022
OBJECTIVES: Disseminated bone marrow (BM) involvement is frequent in multiple myeloma (MM). Whole-body magnetic resonance imaging (wb-MRI) enables to evaluate the whole BM. Reading of such whole-body scans is time-consuming, and yet radiologists can ...
Predictive models for clinical decision making: Deep dives in practical machine learning.
Journal of internal medicine
Apr 25, 2022
The deployment of machine learning for tasks relevant to complementing standard of care and advancing tools for precision health has gained much attention in the clinical community, thus meriting further investigations into its broader use. In an int...
Deep learning-based prediction of molecular cancer biomarkers from tissue slides: A new tool for precision oncology.
Clinical and molecular hepatology
Apr 21, 2022
Molecular tests are necessary to stratify cancer patients for targeted therapy. However, high cost and technical barriers limit the application of these tests, hindering optimal treatment. Recently, deep learning (DL) has been applied to predict mole...
Artificial intelligence to identify genetic alterations in conventional histopathology.
The Journal of pathology
Apr 21, 2022
Precision oncology relies on the identification of targetable molecular alterations in tumor tissues. In many tumor types, a limited set of molecular tests is currently part of standard diagnostic workflows. However, universal testing for all targeta...
Artificial intelligence and machine learning in precision medicine: A paradigm shift in big data analysis.
Progress in molecular biology and translational science
Apr 8, 2022
The integration of artificial intelligence in precision medicine has revolutionized healthcare delivery. Precision medicine identifies the phenotype of particular patients with less-common responses to treatment. Recent studies have demonstrated that...
Effectiveness of Artificial Intelligence for Personalized Medicine in Neoplasms: A Systematic Review.
BioMed research international
Apr 7, 2022
PURPOSE: Artificial intelligence (AI) techniques are used in precision medicine to explore novel genotypes and phenotypes data. The main aims of precision medicine include early diagnosis, screening, and personalized treatment regime for a patient ba...
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