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Stable feature selection for clinical prediction: exploiting ICD tree structure using Tree-Lasso.

Journal of biomedical informatics
Modern healthcare is getting reshaped by growing Electronic Medical Records (EMR). Recently, these records have been shown of great value towards building clinical prediction models. In EMR data, patients' diseases and hospital interventions are capt...

Latching chains in K-nearest-neighbor and modular small-world networks.

Network (Bristol, England)
Latching dynamics retrieve pattern sequences successively by neural adaption and pattern correlation. We have previously proposed a modular latching chain model in Song et al. (2014) to better accommodate the structured transitions in the brain. Diff...

Estimates on compressed neural networks regression.

Neural networks : the official journal of the International Neural Network Society
When the neural element number n of neural networks is larger than the sample size m, the overfitting problem arises since there are more parameters than actual data (more variable than constraints). In order to overcome the overfitting problem, we p...

Quantifying the determinants of outbreak detection performance through simulation and machine learning.

Journal of biomedical informatics
OBJECTIVE: To develop a probabilistic model for discovering and quantifying determinants of outbreak detection and to use the model to predict detection performance for new outbreaks.

Properties and Performance of Imperfect Dual Neural Network-Based kWTA Networks.

IEEE transactions on neural networks and learning systems
The dual neural network (DNN)-based k -winner-take-all ( k WTA) model is an effective approach for finding the k largest inputs from n inputs. Its major assumption is that the threshold logic units (TLUs) can be implemented in a perfect way. However,...

Ensemble learning of inverse probability weights for marginal structural modeling in large observational datasets.

Statistics in medicine
Inverse probability weights used to fit marginal structural models are typically estimated using logistic regression. However, a data-adaptive procedure may be able to better exploit information available in measured covariates. By combining predicti...

Is extreme learning machine feasible? A theoretical assessment (part II).

IEEE transactions on neural networks and learning systems
An extreme learning machine (ELM) can be regarded as a two-stage feed-forward neural network (FNN) learning system that randomly assigns the connections with and within hidden neurons in the first stage and tunes the connections with output neurons i...

Diagnostic classification of specific phobia subtypes using structural MRI data: a machine-learning approach.

Journal of neural transmission (Vienna, Austria : 1996)
While neuroimaging research has advanced our knowledge about fear circuitry dysfunctions in anxiety disorders, findings based on diagnostic groups do not translate into diagnostic value for the individual patient. Machine-learning generates predictiv...

Controlling motion prediction errors in radiotherapy with relevance vector machines.

International journal of computer assisted radiology and surgery
PURPOSE: Robotic radiotherapy can precisely ablate moving tumors when time latencies have been compensated. Recently, relevance vector machines (RVM), a probabilistic regression technique, outperformed six other prediction algorithms for respiratory ...

Classifier calibration using splined empirical probabilities in clinical risk prediction.

Health care management science
The aims of supervised machine learning (ML) applications fall into three broad categories: classification, ranking, and calibration/probability estimation. Many ML methods and evaluation techniques relate to the first two. Nevertheless, there are ma...