SUMMARY: Disease ontology (DO) annotates human genes in the context of disease. DO is important annotation in translating molecular findings from high-throughput data to clinical relevance. DOSE is an R package providing semantic similarity computati...
RATIONALE AND OBJECTIVES: The objectives are: 1) to introduce a simple and efficient method for extracting region of interest (ROI) values from a Picture Archiving and Communication System (PACS) viewer using optical character recognition (OCR) softw...
Journal of the American Medical Informatics Association : JAMIA
Apr 1, 2025
OBJECTIVE: The objectives of this study are to synthesize findings from recent research of retrieval-augmented generation (RAG) and large language models (LLMs) in biomedicine and provide clinical development guidelines to improve effectiveness.
Database : the journal of biological databases and curation
Jan 22, 2025
Ontologies and knowledge graphs (KGs) are general-purpose computable representations of some domain, such as human anatomy, and are frequently a crucial part of modern information systems. Most of these structures change over time, incorporating new ...
Studies in health technology and informatics
Nov 22, 2024
The Arden Syntax is a language designed for the encoding of medical knowledge into clinical decision support systems. Its evolution is overseen by Health Level 7. A significant enhancement in its new version 3.0 is the incorporation of FHIR for data ...
Studies in health technology and informatics
Aug 22, 2024
Electrocardiogram (ECG) is one of the reference cardiovascular diagnostic exams. However, the ECG signal is very prone to being distorted through different sources of artifacts that can later interfere with the diagnostic. For this reason, signal qua...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2023
Discovering molecular biomarkers for predicting patient survival outcomes is an essential step toward improving prognosis and therapeutic decision-making in the treatment of severe diseases such as cancer. Due to the high-dimensionality nature of omi...
MOTIVATION: In multi-cohort machine learning studies, it is critical to differentiate between effects that are reproducible across cohorts and those that are cohort-specific. Multi-task learning (MTL) is a machine learning approach that facilitates t...