AIMC Topic: Pseudopodia

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filoVision - using deep learning and tip markers to automate filopodia analysis.

Journal of cell science Feb 27, 2024
Filopodia are slender, actin-filled membrane projections used by various cell types for environment exploration. Analyzing filopodia often involves visualizing them using actin, filopodia tip or membrane markers. Due to the diversity of cell types th...
Animals Deep Learning Mammals Actins Pseudopodia
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Effect of Oxidized LDL on Platelet Shape, Spreading, and Migration Investigated with Deep Learning Platelet Morphometry.

Cells Oct 28, 2021
Platelets are functionally versatile blood cells involved in thrombosis, hemostasis, atherosclerosis, and immune response. Platelet interaction with the immediate microenvironment in blood, vasculature, and tissues alters platelet morphology. The qua...
Humans Deep Learning Cell Movement Lipoproteins, LDL Extracellular Matrix Blood Platelets Cell Shape Touch Pseudopodia
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3-D Quantification of Filopodia in Motile Cancer Cells.

IEEE transactions on medical imaging Oct 5, 2018
We present a 3D bioimage analysis workflow to quantitatively analyze single, actin-stained cells with filopodial protrusions of diverse structural and temporal attributes, such as number, length, thickness, level of branching, and lifetime, in time-l...
Humans Neural Networks, Computer Algorithms Neoplasms Spatio-Temporal Analysis Imaging, Three-Dimensional Image Processing, Computer-Assisted Lung Neoplasms Adenocarcinoma Cell Line Pseudopodia
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Deconvolution of subcellular protrusion heterogeneity and the underlying actin regulator dynamics from live cell imaging.

Nature communications Apr 27, 2018
Cell protrusion is morphodynamically heterogeneous at the subcellular level. However, the mechanism of cell protrusion has been understood based on the ensemble average of actin regulator dynamics. Here, we establish a computational framework called ...
Humans Machine Learning Software Animals Cell Line, Tumor Cell Movement Cluster Analysis Cell Line Models, Biological Phosphoproteins Indoles Actins Cell Adhesion Molecules Actin Cytoskeleton Intravital Microscopy Actin-Related Protein 2-3 Complex Microfilament Proteins Potoroidae Pseudopodia Vasodilator-Stimulated Phosphoprotein
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