AIMC Topic: Quality Control

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An empirical analysis of ontology reuse in BioPortal.

Journal of biomedical informatics
Biomedical ontologies often reuse content (i.e., classes and properties) from other ontologies. Content reuse enables a consistent representation of a domain and reusing content can save an ontology author significant time and effort. Prior studies h...

acdc - Automated Contamination Detection and Confidence estimation for single-cell genome data.

BMC bioinformatics
BACKGROUND: A major obstacle in single-cell sequencing is sample contamination with foreign DNA. To guarantee clean genome assemblies and to prevent the introduction of contamination into public databases, considerable quality control efforts are put...

Supporting the analysis of ontology evolution processes through the combination of static and dynamic scaling functions in OQuaRE.

Journal of biomedical semantics
BACKGROUND: The biomedical community has now developed a significant number of ontologies. The curation of biomedical ontologies is a complex task and biomedical ontologies evolve rapidly, so new versions are regularly and frequently published in ont...

Machine Learning Approach to Automated Quality Identification of Human Induced Pluripotent Stem Cell Colony Images.

Computational and mathematical methods in medicine
The focus of this research is on automated identification of the quality of human induced pluripotent stem cell (iPSC) colony images. iPS cell technology is a contemporary method by which the patient's cells are reprogrammed back to stem cells and ar...

Utilizing a structural meta-ontology for family-based quality assurance of the BioPortal ontologies.

Journal of biomedical informatics
An Abstraction Network is a compact summary of an ontology's structure and content. In previous research, we showed that Abstraction Networks support quality assurance (QA) of biomedical ontologies. The development of an Abstraction Network and its a...

Fit-for-purpose chromatographic method for the determination of amikacin in human plasma for the dosage control of patients.

Talanta
In this paper, a simple, rapid and sensitive method based on liquid chromatography with fluorimetric detection (HPLC-FLD) for the determination of amikacin (AMK) in human plasma is developed. Determination is performed by pre-column derivatization of...

Investigation of six bioactive anthraquinones in slimming tea by accelerated solvent extraction and high performance capillary electrophoresis with diode-array detection.

Food chemistry
A rapid and effective method for effective separation and rapid simultaneous determination of six bioactive anthraquinones by capillary zone electrophoresis was developed. An accelerated solvent extraction procedure was used for the extraction of ant...

Quality assurance of the gene ontology using abstraction networks.

Journal of bioinformatics and computational biology
The gene ontology (GO) is used extensively in the field of genomics. Like other large and complex ontologies, quality assurance (QA) efforts for GO's content can be laborious and time consuming. Abstraction networks (AbNs) are summarization networks ...