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Radiotherapy Dosage

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Implementation and evaluation of an intelligent automatic treatment planning robot for prostate cancer stereotactic body radiation therapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
PURPOSE: We previously developed a virtual treatment planner (VTP), an artificial intelligence robot, operating a treatment planning system (TPS). Using deep reinforcement learning guided by human knowledge, we trained the VTP to autonomously adjust ...

A deep learning-based approach for statistical robustness evaluation in proton therapy treatment planning: a feasibility study.

Physics in medicine and biology
. Robustness evaluation is critical in particle radiotherapy due to its susceptibility to uncertainties. However, the customary method for robustness evaluation only considers a few uncertainty scenarios, which are insufficient to provide a consisten...

Deep learning prediction of post-SBRT liver function changes and NTCP modeling in hepatocellular carcinoma based on DGAE-MRI.

Medical physics
BACKGROUND: Stereotactic body radiation therapy (SBRT) produces excellent local control for patients with hepatocellular carcinoma (HCC). However, the risk of toxicity for normal liver tissue is still a limiting factor. Normal tissue complication pro...

TrDosePred: A deep learning dose prediction algorithm based on transformers for head and neck cancer radiotherapy.

Journal of applied clinical medical physics
BACKGROUND: Intensity-Modulated Radiation Therapy (IMRT) has been the standard of care for many types of tumors. However, treatment planning for IMRT is a time-consuming and labor-intensive process.

Evaluation of auto-segmentation for brachytherapy of postoperative cervical cancer using deep learning-based workflow.

Physics in medicine and biology
. The purpose of this study was to evaluate the accuracy of brachytherapy (BT) planning structures derived from Deep learning (DL) based auto-segmentation compared with standard manual delineation for postoperative cervical cancer.. We introduced a c...

Patient-specific three-dimensional dose distribution prediction via deep learning for prostate cancer therapy: Improvement with the structure loss.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: Deep learning (DL)-based dose distribution prediction can potentially reduce the cost of inverse planning process. We developed and introduced a structure-focused loss (L) for 3D dose prediction to improve prediction accuracy. This study inv...

A novel mathematical model to generate semi-automated optimal IMRT treatment plan based on predicted 3D dose distribution and prescribed dose.

Medical physics
BACKGROUND: In recent years, with the development of artificial intelligence and deep learning techniques, it has become possible to predict the three-dimensional distribution dose (3D ) of a new patient based on the treatment plans of similar recent...

3D dose prediction for Gamma Knife radiosurgery using deep learning and data modification.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: To develop a machine learning-based, 3D dose prediction methodology for Gamma Knife (GK) radiosurgery. The methodology accounts for cases involving targets of any number, size, and shape.

Deep Learning-Based Dose Prediction for Automated, Individualized Quality Assurance of Head and Neck Radiation Therapy Plans.

Practical radiation oncology
PURPOSE: This study aimed to use deep learning-based dose prediction to assess head and neck (HN) plan quality and identify suboptimal plans.

A generalization performance study on the boosting radiotherapy dose calculation engine based on super-resolution.

Zeitschrift fur medizinische Physik
PURPOSE: During the radiation treatment planning process, one of the time-consuming procedures is the final high-resolution dose calculation, which obstacles the wide application of the emerging online adaptive radiotherapy techniques (OLART). There ...