AIMC Topic: Radiotherapy Dosage

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Deep learning-based dose prediction to improve the plan quality of volumetric modulated arc therapy for gynecologic cancers.

Medical physics
BACKGROUND: In recent years, deep-learning models have been used to predict entire three-dimensional dose distributions. However, the usability of dose predictions to improve plan quality should be further investigated.

Proton range uncertainty caused by synthetic computed tomography generated with deep learning from pelvic magnetic resonance imaging.

Acta oncologica (Stockholm, Sweden)
BACKGROUND: In proton therapy, it is disputed whether synthetic computed tomography (sCT), derived from magnetic resonance imaging (MRI), permits accurate dose calculations. On the one hand, an MRI-only workflow could eliminate errors caused by, e.g....

Deep learning-based fast denoising of Monte Carlo dose calculation in carbon ion radiotherapy.

Medical physics
BACKGROUND: Plan verification is one of the important steps of quality assurance (QA) in carbon ion radiotherapy. Conventional methods of plan verification are based on phantom measurement, which is labor-intensive and time-consuming. Although the pl...

Deep learning-based detection and classification of multi-leaf collimator modeling errors in volumetric modulated radiation therapy.

Journal of applied clinical medical physics
PURPOSE: The purpose of this study was to create and evaluate deep learning-based models to detect and classify errors of multi-leaf collimator (MLC) modeling parameters in volumetric modulated radiation therapy (VMAT), namely the transmission factor...

Performance assessment of variant UNet-based deep-learning dose engines for MR-Linac-based prostate IMRT plans.

Physics in medicine and biology
. UNet-based deep-learning (DL) architectures are promising dose engines for traditional linear accelerator (Linac) models. Current UNet-based engines, however, were designed differently with various strategies, making it challenging to fairly compar...

Generation of synthetic CT from CBCT using deep learning approaches for head and neck cancer patients.

Biomedical physics & engineering express
To create a synthetic CT (sCT) from daily CBCT using either deep residual U-Net (DRUnet), or conditional generative adversarial network (cGAN) for adaptive radiotherapy planning (ART).First fraction CBCT and planning CT (pCT) were collected from 93 H...

A hybrid method of correcting CBCT for proton range estimation with deep learning and deformable image registration.

Physics in medicine and biology
. This study aimed to develop a novel method for generating synthetic CT (sCT) from cone-beam CT (CBCT) of the abdomen/pelvis with bowel gas pockets to facilitate estimation of proton ranges.. CBCT, the same-day repeat CT, and the planning CT (pCT) o...

Deep learning proton beam range estimation model for quality assurance based on two-dimensional scintillated light distributions in simulations.

Medical physics
BACKGROUND: Many studies have utilized optical camera systems with volumetric scintillators for quality assurances (QA) to estimate the proton beam range. However, previous analytically driven range estimation methods have the difficulty to derive th...

Exploring contrast generalisation in deep learning-based brain MRI-to-CT synthesis.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
BACKGROUND: Synthetic computed tomography (sCT) has been proposed and increasingly clinically adopted to enable magnetic resonance imaging (MRI)-based radiotherapy. Deep learning (DL) has recently demonstrated the ability to generate accurate sCT fro...

Virtual pretreatment patient-specific quality assurance of volumetric modulated arc therapy using deep learning.

Medical physics
BACKGROUND: Automatic patient-specific quality assurance (PSQA) is recently explored using artificial intelligence approaches, and several studies reported the development of machine learning models for predicting the gamma pass rate (GPR) index only...