BACKGROUND: In cancer care, determining the most beneficial treatment technique is a key decision affecting the patient's survival and quality of life. Patient selection for proton therapy (PT) over conventional radiotherapy (XT) currently entails co...
Journal of applied clinical medical physics
May 3, 2023
PURPOSE: In this paper, we compare four novel knowledge-based planning (KBP) algorithms using deep learning to predict three-dimensional (3D) dose distributions of head and neck plans using the same patients' dataset and quantitative assessment metri...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Apr 28, 2023
PURPOSE: We previously developed a virtual treatment planner (VTP), an artificial intelligence robot, operating a treatment planning system (TPS). Using deep reinforcement learning guided by human knowledge, we trained the VTP to autonomously adjust ...
. Robustness evaluation is critical in particle radiotherapy due to its susceptibility to uncertainties. However, the customary method for robustness evaluation only considers a few uncertainty scenarios, which are insufficient to provide a consisten...
BACKGROUND: Stereotactic body radiation therapy (SBRT) produces excellent local control for patients with hepatocellular carcinoma (HCC). However, the risk of toxicity for normal liver tissue is still a limiting factor. Normal tissue complication pro...
Journal of applied clinical medical physics
Mar 3, 2023
BACKGROUND: Intensity-Modulated Radiation Therapy (IMRT) has been the standard of care for many types of tumors. However, treatment planning for IMRT is a time-consuming and labor-intensive process.
. The purpose of this study was to evaluate the accuracy of brachytherapy (BT) planning structures derived from Deep learning (DL) based auto-segmentation compared with standard manual delineation for postoperative cervical cancer.. We introduced a c...
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Feb 10, 2023
PURPOSE: Deep learning (DL)-based dose distribution prediction can potentially reduce the cost of inverse planning process. We developed and introduced a structure-focused loss (L) for 3D dose prediction to improve prediction accuracy. This study inv...
BACKGROUND: In recent years, with the development of artificial intelligence and deep learning techniques, it has become possible to predict the three-dimensional distribution dose (3D ) of a new patient based on the treatment plans of similar recent...
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Jan 30, 2023
PURPOSE: To develop a machine learning-based, 3D dose prediction methodology for Gamma Knife (GK) radiosurgery. The methodology accounts for cases involving targets of any number, size, and shape.
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