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Radiotherapy Dosage

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A plan verification platform for online adaptive proton therapy using deep learning-based Monte-Carlo denoising.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
BACKGROUND PURPOSE: This study focused on developing a fast Monte Carlo (MC) plan verification platform via a deep learning (DL)-based denoising approach. It can maintain the MC dose calculation accuracy while significantly reducing the computation t...

Automated clinical decision support system with deep learning dose prediction and NTCP models to evaluate treatment complications in patients with esophageal cancer.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: This study aims to investigate how accurate our deep learning (DL) dose prediction models for intensity modulated radiotherapy (IMRT) and pencil beam scanning (PBS) treatments, when chained with normal tissue complication prob...

A deep learning approach to generate synthetic CT in low field MR-guided radiotherapy for lung cases.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
INTRODUCTION: This study aims to apply a conditional Generative Adversarial Network (cGAN) to generate synthetic Computed Tomography (sCT) from 0.35 Tesla Magnetic Resonance (MR) images of the thorax.

Development of deep learning chest X-ray model for cardiac dose prediction in left-sided breast cancer radiotherapy.

Scientific reports
Deep inspiration breath-hold (DIBH) is widely used to reduce the cardiac dose in left-sided breast cancer radiotherapy. This study aimed to develop a deep learning chest X-ray model for cardiac dose prediction to select patients with a potentially hi...

A novel multichannel deep learning model for fast denoising of Monte Carlo dose calculations: preclinical applications.

Physics in medicine and biology
In preclinical radiotherapy with kilovolt (kV) x-ray beams, accurate treatment planning is needed to improve the translation potential to clinical trials. Monte Carlo based radiation transport simulations are the gold standard to calculate the absorb...

Fast VMAT planning for prostate radiotherapy: dosimetric validation of a deep learning-based initial segment generation method.

Physics in medicine and biology
. To develop and evaluate a deep learning based fast volumetric modulated arc therapy (VMAT) plan generation method for prostate radiotherapy.. A customized 3D U-Net was trained and validated to predict initial segments at 90 evenly distributed contr...

Deep learning methods for enhancing cone-beam CT image quality toward adaptive radiation therapy: A systematic review.

Medical physics
The use of deep learning (DL) to improve cone-beam CT (CBCT) image quality has gained popularity as computational resources and algorithmic sophistication have advanced in tandem. CBCT imaging has the potential to facilitate online adaptive radiation...

DR-only Carbon-ion radiotherapy treatment planning via deep learning.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: To evaluate the feasibility of patient-specific digital radiography (DR)-only treatment planning for carbon ion radiotherapy in anthropomorphic thorax-and-abdomen phantom and head-and-neck patients.

Machine learning models to predict the delivered positions of Elekta multileaf collimator leaves for volumetric modulated arc therapy.

Journal of applied clinical medical physics
PURPOSE: Accurate positioning of multileaf collimator (MLC) leaves during volumetric modulated arc therapy (VMAT) is essential for accurate treatment delivery. We developed a linear regression, support vector machine, random forest, extreme gradient ...

Treatment plan prediction for lung IMRT using deep learning based fluence map generation.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: Recently, it has been shown that automated treatment planning can be executed by direct fluence prediction from patient anatomy using convolutional neural networks. Proof of principle publications utilise a fixed dose prescription and fixed ...