AIMC Topic: Radiotherapy Planning, Computer-Assisted

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Transformer-Integrated Hybrid Convolutional Neural Network for Dose Prediction in Nasopharyngeal Carcinoma Radiotherapy.

Journal of imaging informatics in medicine
Radiotherapy is recognized as the major treatment of nasopharyngeal carcinoma. Rapid and accurate dose prediction can improve the efficiency of the treatment planning process and the quality of radiotherapy plans. Currently, deep learning-based metho...

OSAIRIS: Lessons Learned From the Hospital-Based Implementation and Evaluation of an Open-Source Deep-Learning Model for Radiotherapy Image Segmentation.

Clinical oncology (Royal College of Radiologists (Great Britain))
Several studies report the benefits and accuracy of using autosegmentation for organ at risk (OAR) outlining in radiotherapy treatment planning. Typically, evaluations focus on accuracy metrics, and other parameters such as perceived utility and safe...

Achieving accurate prostate auto-segmentation on CT in the absence of MR imaging.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND: Magnetic resonance imaging (MRI) is considered the gold standard for prostate segmentation. Computed tomography (CT)-based segmentation is prone to observer bias, potentially overestimating the prostate volume by ∼ 30 % compared to MRI. H...

Clinical target volume (CTV) automatic delineation using deep learning network for cervical cancer radiotherapy: A study with external validation.

Journal of applied clinical medical physics
PURPOSE: To explore the accuracy and feasibility of a proposed deep learning (DL) algorithm for clinical target volume (CTV) delineation in cervical cancer radiotherapy and evaluate whether it can perform well in external cervical cancer and endometr...

Deep Learning-Based Synthetic Computed Tomography for Low-Field Brain Magnetic Resonance-Guided Radiation Therapy.

International journal of radiation oncology, biology, physics
PURPOSE: Magnetic resonance (MR)-guided radiation therapy enables online adaptation to address intra- and interfractional changes. To address the need of high-fidelity synthetic computed tomography (synCT) required for dose calculation, we developed ...

A deep learning-informed interpretation of why and when dose metrics outside the PTV can affect the risk of distant metastasis in SBRT NSCLC patients.

Radiation oncology (London, England)
PURPOSE: Recent papers suggested a correlation between the risk of distant metastasis (DM) and dose outside the PTV, though conclusions in different publications conflicted. This study resolves these conflicts and provides a compelling explanation of...

Deep learning-based segmentation for high-dose-rate brachytherapy in cervical cancer using 3D Prompt-ResUNet.

Physics in medicine and biology
To develop and evaluate a 3D Prompt-ResUNet module that utilized the prompt-based model combined with 3D nnUNet for rapid and consistent autosegmentation of high-risk clinical target volume (HRCTV) and organ at risk (OAR) in high-dose-rate brachyther...

Quantifying and visualising uncertainty in deep learning-based segmentation for radiation therapy treatment planning: What do radiation oncologists and therapists want?

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: During the ESTRO 2023 physics workshop on "AI for the fully automated radiotherapy treatment chain", the topic of deep learning (DL) segmentation was discussed. Despite its widespread use in radiotherapy, the time needed to ev...

Artificial intelligence (AI) applications in improvement of IMRT and VMAT radiotherapy treatment planning processes: A systematic review.

Radiography (London, England : 1995)
INTRODUCTION: Radiotherapy is a common option in the treatment of many types of cancer. Intensity-Modulated Radiation Therapy (IMRT) and Volumetric-Modulated Arc Therapy (VMAT) are the latest radiotherapy techniques. However, clinicians face problems...

Deep evidential learning for radiotherapy dose prediction.

Computers in biology and medicine
BACKGROUND: As we navigate towards integrating deep learning methods in the real clinic, a safety concern lies in whether and how the model can express its own uncertainty when making predictions. In this work, we present a novel application of an un...