AIMC Topic: Radiotherapy Planning, Computer-Assisted

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Towards improved prescription metrics in novel radiotherapy techniques: a machine learning study.

Physics in medicine and biology
FLASH radiotherapy (RT), microbeam RT (MRT) and minibeam RT (MBRT) are novel RT techniques that have been shown to reduce normal tissue complication probabilities, by modulating the dose distributions through different parameters in space and time. T...

Evaluating the dosimetric and positioning accuracy of a deep learning based synthetic-CT model for liver radiotherapy treatment planning.

Biomedical physics & engineering express
An MRI-only workflow requires synthetic computed tomography (sCT) images to enable dose calculation. This study evaluated the dosimetric and patient positioning accuracy of deep learning-generated sCT for liver radiotherapy.sCT images were generated ...

Portal dose image prediction using Monte Carlo generated transmission energy fluence maps of dynamic radiotherapy treatment plans: a deep learning approach.

Biomedical physics & engineering express
This work aims to develop and investigate the feasibility of a hybrid model combining Monte Carlo (MC) simulations and deep learning (DL) to predict electronic portal imaging device (EPID) images based on MC-generated exit phase space energy fluence ...

Rapid dose prediction for lung CyberKnife radiotherapy plans utilizing a deep learning approach by incorporating dosimetric features delivered by noncoplanar beams.

Biomedical physics & engineering express
. The dose distribution of lung cancer patients treated with the CyberKnife (CK) system is influenced by various factors, including tumor location and the direction of CK beams. The objective of this study is to present a deep learning approach that ...

Open-source deep-learning models for segmentation of normal structures for prostatic and gynecological high-dose-rate brachytherapy: Comparison of architectures.

Journal of applied clinical medical physics
BACKGROUND: The use of deep learning-based auto-contouring algorithms in various treatment planning services is increasingly common. There is a notable deficit of commercially or publicly available models trained on large or diverse datasets containi...

An isodose-constrained automatic treatment planning strategy using a multicriteria predicted dose rating.

Medical physics
BACKGROUND: Previous knowledge-based planning studies have demonstrated the feasibility of predicting three-dimensional photon dose distributions and subsequently generating treatment plans. The steepness of dose fall-off represents a critical metric...

Deep-learning synthetized 4DCT from 4DMRI of the abdominal site in carbon-ion radiotherapy.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: To investigate the feasibility of deep-learning-based synthetic 4DCT (4D-sCT) generation from 4DMRI data of abdominal patients undergoing Carbon Ion Radiotherapy (CIRT).

An extension to the OVH concept for knowledge-based dose volume histogram prediction in lung tumor volumetric-modulated arc therapy.

Journal of applied clinical medical physics
PURPOSE: Volumetric-modulated arc therapy (VMAT) treatment planning allows a compromise between a sufficient coverage of the planning target volume (PTV) and a simultaneous sparing of organs-at-risk (OARs). Particularly in the case of lung tumors, de...

Trade-off of different deep learning-based auto-segmentation approaches for treatment planning of pediatric craniospinal irradiation autocontouring of OARs for pediatric CSI.

Medical physics
BACKGROUND: As auto-segmentation tools become integral to radiotherapy, more commercial products emerge. However, they may not always suit our needs. One notable example is the use of adult-trained commercial software for the contouring of organs at ...

Clinically applicable semi-supervised learning framework for multiple organs at risk and tumor delineation in lung cancer brachytherapy.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: The generalization ability of deep learning-based automatic segmentation techniques for lung cancer in practical clinical applications remains under-validated. We reported an investigation that validated a robust semi-supervised conditional ...