FLASH radiotherapy (RT), microbeam RT (MRT) and minibeam RT (MBRT) are novel RT techniques that have been shown to reduce normal tissue complication probabilities, by modulating the dose distributions through different parameters in space and time. T...
An MRI-only workflow requires synthetic computed tomography (sCT) images to enable dose calculation. This study evaluated the dosimetric and patient positioning accuracy of deep learning-generated sCT for liver radiotherapy.sCT images were generated ...
This work aims to develop and investigate the feasibility of a hybrid model combining Monte Carlo (MC) simulations and deep learning (DL) to predict electronic portal imaging device (EPID) images based on MC-generated exit phase space energy fluence ...
. The dose distribution of lung cancer patients treated with the CyberKnife (CK) system is influenced by various factors, including tumor location and the direction of CK beams. The objective of this study is to present a deep learning approach that ...
Journal of applied clinical medical physics
Apr 5, 2025
BACKGROUND: The use of deep learning-based auto-contouring algorithms in various treatment planning services is increasingly common. There is a notable deficit of commercially or publicly available models trained on large or diverse datasets containi...
BACKGROUND: Previous knowledge-based planning studies have demonstrated the feasibility of predicting three-dimensional photon dose distributions and subsequently generating treatment plans. The steepness of dose fall-off represents a critical metric...
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Apr 4, 2025
PURPOSE: To investigate the feasibility of deep-learning-based synthetic 4DCT (4D-sCT) generation from 4DMRI data of abdominal patients undergoing Carbon Ion Radiotherapy (CIRT).
Journal of applied clinical medical physics
Apr 3, 2025
PURPOSE: Volumetric-modulated arc therapy (VMAT) treatment planning allows a compromise between a sufficient coverage of the planning target volume (PTV) and a simultaneous sparing of organs-at-risk (OARs). Particularly in the case of lung tumors, de...
BACKGROUND: As auto-segmentation tools become integral to radiotherapy, more commercial products emerge. However, they may not always suit our needs. One notable example is the use of adult-trained commercial software for the contouring of organs at ...
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Apr 1, 2025
PURPOSE: The generalization ability of deep learning-based automatic segmentation techniques for lung cancer in practical clinical applications remains under-validated. We reported an investigation that validated a robust semi-supervised conditional ...
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