BACKGROUND: Currently there is an ever increasing interest in Lu-177 targeted radionuclide therapies, which target neuro-endocrine and prostate tumours. For a patient-specific treatment, an individual dosimetry based on SPECT/CT imaging is necessary....
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Oct 17, 2020
PURPOSE: Artificial intelligence (AI) can play a significant role in Magnetic Resonance guided Radiotherapy (MRgRT), especially to speed up the online adaptive workflow. The aim of this study is to set up a Deep Learning (DL) approach able to generat...
The aim of dose calculation algorithm research is to improve the calculation accuracy while maximizing the calculation efficiency. In this study, the three-dimensional distribution of total energy release per unit mass (TERMA) and the electron densit...
PURPOSE: To develop a deep learning-based model to predict achievable dose-volume histograms (DVHs) of organs at risk (OARs) for automation of inverse planning.
International journal of radiation oncology, biology, physics
Oct 14, 2020
PURPOSE: To develop a deep learning model that generates consistent, high-quality lymph node clinical target volumes (CTV) contours for head and neck cancer (HNC) patients, as an integral part of a fully automated radiation treatment planning workflo...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Oct 8, 2020
PURPOSE: The delineation of the clinical target volume (CTV) is a crucial, laborious and subjective step in cervical cancer radiotherapy. The aim of this study was to propose and evaluate a novel end-to-end convolutional neural network (CNN) for full...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Oct 7, 2020
PURPOSE: To assess the feasibility of magnetic resonance imaging (MRI)-only treatment planning for photon and proton radiotherapy in children with abdominal tumours.
We developed a generative adversarial network (GAN)-based deep learning approach to estimate the multileaf collimator (MLC) aperture and corresponding monitor units (MUs) from a given 3D dose distribution. The proposed design of the adversarial netwo...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Sep 28, 2020
Manual segmentation is the gold standard method for radiation therapy planning; however, it is time-consuming and prone to inter- and intra-observer variation, giving rise to interests in auto-segmentation methods. We evaluated the feasibility of dee...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Sep 23, 2020
BACKGROUND AND PURPOSE: To enable accurate magnetic resonance imaging (MRI)-based dose calculations, synthetic computed tomography (sCT) images need to be generated. We aim at assessing the feasibility of dose calculations from MRI acquired with a he...