Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
38307160
BACKGROUND: We employed deep learning to automatically detect myocardial bone-seeking uptake as a marker of transthyretin cardiac amyloid cardiomyopathy (ATTR-CM) in patients undergoing 99mTc-pyrophosphate (PYP) or hydroxydiphosphonate (HDP) single-p...
BACKGROUND: The application of deep learning methods in rapid bone scintigraphy is increasingly promising for minimizing the duration of SPECT examinations. Recent works showed several deep learning models based on simulated data for the synthesis of...
BACKGROUND: Deformable registration is required to generate a time-integrated activity (TIA) map which is essential for voxel-based dosimetry. The conventional iterative registration algorithm using anatomical images (e.g., computed tomography (CT)) ...
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
38548351
Heart failure (HF) is a leading cause of morbidity and mortality in the United States and worldwide, with a high associated economic burden. This study aimed to assess whether artificial intelligence models incorporating clinical, stress test, and im...
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
38637141
With the development of new radiopharmaceutical therapies, quantitative SPECT/CT has progressively emerged as a crucial tool for dosimetry. One major obstacle of SPECT is its poor resolution, which results in blurring of the activity distribution. Es...
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
38724278
Transthyretin cardiac amyloidosis (ATTR CA) is increasingly recognized as a cause of heart failure in older patients, with Tc-pyrophosphate imaging frequently used to establish the diagnosis. Visual interpretation of SPECT images is the gold standard...
INTRODUCTION: Attenuation correction (AC) is necessary for accurate assessment of radioactive distribution in single photon emission computed tomography (SPECT). The method of computed tomography-based AC (CTAC) is widely used because of its accuracy...
Deep learning (DL) is becoming increasingly important in generating attenuation maps for accurate attenuation correction (AC) in cardiac perfusion SPECT imaging. Typically, DL models take inputs from initial reconstructed SPECT images, which are perf...
PURPOSE: To train and validate machine learning-derived clinical decision algorithm (CDA) for the diagnosis of hyperfunctioning parathyroid glands using preoperative variables to facilitate surgical planning.