AIMC Topic: Radiotherapy Planning, Computer-Assisted

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Performance assessment of a new optimization system for robotic SBRT MLC-based plans.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: To assess the performance of a new optimization system, VOLO, for CyberKnife MLC-based SBRT plans in comparison with the existing Sequential optimizer.

Many-isocenter optimization for robotic radiotherapy.

Physics in medicine and biology
Despite significant dosimetric gains, clinical implementation of the 4π non-coplanar radiotherapy on the widely available C-arm gantry system is hindered by limited clearance, and the need to perform complex coordinated gantry and couch motion. A rob...

Automatic delineation of the clinical target volume and organs at risk by deep learning for rectal cancer postoperative radiotherapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: Manual delineation of clinical target volumes (CTVs) and organs at risk (OARs) is time-consuming, and automatic contouring tools lack clinical validation. We aimed to construct and validate the use of convolutional neural netw...

Deep DoseNet: a deep neural network for accurate dosimetric transformation between different spatial resolutions and/or different dose calculation algorithms for precision radiation therapy.

Physics in medicine and biology
The purpose of this work is to introduce a novel deep learning strategy to obtain highly accurate dose plan by transforming from a dose distribution calculated using a low-cost algorithm (or algorithmic settings). 25 168 slices of dose distribution a...

User-controlled pipelines for feature integration and head and neck radiation therapy outcome predictions.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: Precision cancer medicine is dependent on accurate prediction of disease and treatment outcome, requiring integration of clinical, imaging and interventional knowledge. User controlled pipelines are capable of feature integration with varied...

Prediction of the individual multileaf collimator positional deviations during dynamic IMRT delivery priori with artificial neural network.

Medical physics
PURPOSES: Multileaf collimator (MLC) positional accuracy during dynamic intensity modulation radiotherapy (IMRT) delivery is crucial for safe and accurate patient treatment. The deviations of individual leaf positions from its intended positions can ...

Integration of the M6 Cyberknife in the Moderato Monte Carlo platform and prediction of beam parameters using machine learning.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: This work describes the integration of the M6 Cyberknife in the Moderato Monte Carlo platform, and introduces a machine learning method to accelerate the modelling of a linac.

Convolutional neural network enhancement of fast-scan low-dose cone-beam CT images for head and neck radiotherapy.

Physics in medicine and biology
To improve image quality and CT number accuracy of fast-scan low-dose cone-beam computed tomography (CBCT) through a deep-learning convolutional neural network (CNN) methodology for head-and-neck (HN) radiotherapy. Fifty-five paired CBCT and CT image...

Knowledge-Based Tradeoff Hyperplanes for Head and Neck Treatment Planning.

International journal of radiation oncology, biology, physics
PURPOSE: To develop a tradeoff hyperplane model to facilitate tradeoff decision-making before inverse planning.

A fast deep learning approach for beam orientation optimization for prostate cancer treated with intensity-modulated radiation therapy.

Medical physics
PURPOSE: Beam orientation selection, whether manual or protocol-based, is the current clinical standard in radiation therapy treatment planning, but it is tedious and can yield suboptimal results. Many algorithms have been designed to optimize beam o...