AIMC Topic: RNA, Long Noncoding
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[Screening of characteristic genes of salivary gland adenoid cystic carcinoma based on weighted co-expression network and machine learning].
Shanghai kou qiang yi xue = Shanghai journal of stomatology
Dec 1, 2024
PURPOSE: To identify potential biomarkers of salivary gland adenoid cystic carcinoma to further understand the potential pathogenesis of adenoid cystic carcinoma.
Introducing TEC-LncMir for prediction of lncRNA-miRNA interactions through deep learning of RNA sequences.
Briefings in bioinformatics
Nov 22, 2024
The interactions between long noncoding RNA (lncRNA) and microRNA (miRNA) play critical roles in life processes, highlighting the necessity to enhance the performance of state-of-the-art models. Here, we introduced TEC-LncMir, a novel approach for pr...
FunlncModel: integrating multi-omic features from upstream and downstream regulatory networks into a machine learning framework to identify functional lncRNAs.
Briefings in bioinformatics
Nov 22, 2024
Accumulating evidence indicates that long noncoding RNAs (lncRNAs) play important roles in molecular and cellular biology. Although many algorithms have been developed to reveal their associations with complex diseases by using downstream targets, th...
A comprehensive survey on deep learning-based identification and predicting the interaction mechanism of long non-coding RNAs.
Briefings in functional genomics
Jul 19, 2024
Long noncoding RNAs (lncRNAs) have been discovered to be extensively involved in eukaryotic epigenetic, transcriptional, and post-transcriptional regulatory processes with the advancements in sequencing technology and genomics research. Therefore, th...
Evolutionary learning-derived lncRNA signature with biomarker discovery for predicting stage of colon adenocarcinoma.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2024
In recent years, long non-coding RNAs (lncRNAs) have emerged as potential regulators of biological processes and genes, with the potential to serve as valuable biomarkers for cancer diagnosis and prognosis prediction. This work proposes an evolutiona...
HRGCNLDA: Forecasting of lncRNA-disease association based on hierarchical refinement graph convolutional neural network.
Mathematical biosciences and engineering : MBE
Feb 29, 2024
Long non-coding RNA (lncRNA) is considered to be a crucial regulator involved in various human biological processes, including the regulation of tumor immune checkpoint proteins. It has great potential as both a cancer biomolecular biomarker and ther...
Deqformer: high-definition and scalable deep learning probe design method.
Briefings in bioinformatics
Jan 22, 2024
Target enrichment sequencing techniques are gaining widespread use in the field of genomics, prized for their economic efficiency and swift processing times. However, their success depends on the performance of probes and the evenness of sequencing d...
BioKA: a curated and integrated biomarker knowledgebase for animals.
Nucleic acids research
Jan 5, 2024
Biomarkers play an important role in various area such as personalized medicine, drug development, clinical care, and molecule breeding. However, existing animals' biomarker resources predominantly focus on human diseases, leaving a significant gap i...
Prediction of LncRNA-protein Interactions Using Auto-Encoder, SE-ResNet Models and Transfer Learning.
MicroRNA (Shariqah, United Arab Emirates)
Jan 1, 2024
BACKGROUND: Long non-coding RNA (lncRNA) plays a crucial role in various biological processes, and mutations or imbalances of lncRNAs can lead to several diseases, including cancer, Prader-Willi syndrome, autism, Alzheimer's disease, cartilage-hair h...
Machine Learning-derived Multi-omics Prognostic Signature of Pyroptosis-related lncRNA with Regard to ZKSCAN2-DT and Tumor Immune Infiltration in Colorectal Cancer.
Combinatorial chemistry & high throughput screening
Jan 1, 2024
BACKGROUND: Colorectal cancer (CRC) has become the most prevalent gastrointestinal malignant tumor, ranking third (10.2%) in incidence and second (9.2%) in death among all malignancies globally. The most common histological subtype of CRC is colon ad...
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