AIMC Topic: RNA, Small Nucleolar

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Identifying Associations Between Small Nucleolar RNAs and Diseases via Graph Convolutional Network and Attention Mechanism.

IEEE journal of biomedical and health informatics Dec 5, 2024
Research has shown that small nucleolar RNAs (snoRNAs) play crucial roles in various biological processes, and understanding disease pathogenesis by studying their relationship with diseases is beneficial. Currently, known associations are insufficie...
Humans Neural Networks, Computer Algorithms Computational Biology RNA, Small Nucleolar
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Analysis of Expression Pattern of snoRNAs in Different Cancer Types with Machine Learning Algorithms.

International journal of molecular sciences May 2, 2019
Small nucleolar RNAs (snoRNAs) are a new type of functional small RNAs involved in the chemical modifications of rRNAs, tRNAs, and small nuclear RNAs. It is reported that they play important roles in tumorigenesis via various regulatory modes. snoRNA...
Humans Machine Learning Algorithms Neoplasms Gene Expression Regulation, Neoplastic Support Vector Machine Monte Carlo Method RNA, Small Nucleolar
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SnoReport 2.0: new features and a refined Support Vector Machine to improve snoRNA identification.

BMC bioinformatics Dec 15, 2016
BACKGROUND: snoReport uses RNA secondary structure prediction combined with machine learning as the basis to identify the two main classes of small nucleolar RNAs, the box H/ACA snoRNAs and the box C/D snoRNAs. Here, we present snoReport 2.0, which s...
Humans Animals Computational Biology Support Vector Machine Base Sequence Eukaryota Molecular Sequence Data RNA, Small Nucleolar Vertebrates
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GBDTSVM: Combined Support Vector Machine and Gradient Boosting Decision Tree Framework for efficient snoRNA-disease association prediction.

Computers in biology and medicine Jun 1, 2025
Small nucleolar RNAs (snoRNAs) are increasingly recognized for their critical role in the pathogenesis and characterization of various human diseases. Consequently, the precise identification of snoRNA-disease associations (SDAs) is essential for the...
Humans Computational Biology Support Vector Machine Decision Trees RNA, Small Nucleolar
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Convolutional neural networks for classification of alignments of non-coding RNA sequences.

Bioinformatics (Oxford, England) Jul 1, 2018
MOTIVATION: The convolutional neural network (CNN) has been applied to the classification problem of DNA sequences, with the additional purpose of motif discovery. The training of CNNs with distributed representations of four nucleotides has successf...
Humans Neural Networks, Computer Software Male Protein Binding Computational Biology Adenocarcinoma Cluster Analysis MicroRNAs Prostatic Neoplasms Nucleic Acid Conformation RNA, Transfer Binding Sites RNA, Untranslated RNA, Small Nucleolar
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