AIMC Topic: S100 Proteins

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Comprehensive analysis of single-cell and bulk transcriptome unravels immune landscape of atherosclerosis and develops a S100 family based-diagnostic model.

Computational biology and chemistry Mar 25, 2025
BACKGROUND: The S100 family of calcium-binding proteins (S100s) had been tightly related to the biological processes of various cardiovascular diseases. This study aims to investigate the expression of S100s in Atherosclerosis (AS) and explore their ...
Humans Gene Expression Profiling Transcriptome Single-Cell Analysis S100 Proteins Atherosclerosis
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Integrating single cell analysis and machine learning methods reveals stem cell-related gene S100A10 as an important target for prediction of liver cancer diagnosis and immunotherapy.

Frontiers in immunology Jan 7, 2025
BACKGROUND: Hepatocellular carcinoma (LIHC) poses a significant health challenge worldwide, primarily due to late-stage diagnosis and the limited effectiveness of current therapies. Cancer stem cells are known to play a role in tumor development, met...
Humans Machine Learning Prognosis Biomarkers, Tumor Gene Expression Profiling Liver Neoplasms Carcinoma, Hepatocellular Single-Cell Analysis Immunotherapy Gene Expression Regulation, Neoplastic Neoplastic Stem Cells S100 Proteins
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