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Sarcopenia

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Identifying semaphorin 3C as a biomarker for sarcopenia and coronary artery disease via bioinformatics and machine learning.

Archives of gerontology and geriatrics
OBJECTIVE: Sarcopenia not only affects patients' quality of life but also may exacerbate the pathological processes of coronary artery disease (CAD). This study aimed to identify potential biomarkers to improve the combined diagnosis and treatment of...

Artificial intelligence for body composition assessment focusing on sarcopenia.

Scientific reports
This study aimed to address the limitations of conventional methods for measuring skeletal muscle mass for sarcopenia diagnosis by introducing an artificial intelligence (AI) system for direct computed tomography (CT) analysis. The primary focus was ...

Prediction of sarcopenia at different time intervals: an interpretable machine learning analysis of modifiable factors.

BMC geriatrics
OBJECTIVES: This study aims to develop sarcopenia risk prediction models for Chinese older adults at different time intervals and to identify and compare modifiable factors contributing to sarcopenia development.

Impact of Hydroxy-Methyl-Butyrate Supplementation on Malnourished Patients Assessed Using AI-Enhanced Ultrasound Imaging.

Journal of cachexia, sarcopenia and muscle
BACKGROUND: This study aimed to evaluate the effects of an oral nutritional supplement (ONS) enriched with hydroxy-methyl-butyrate (HMB) in subjects with disease-related malnutrition (DRM) and to monitor these effects with an ultrasound Imaging Syste...

Machine learning based on nutritional assessment to predict adverse events in older inpatients with possible sarcopenia.

Aging clinical and experimental research
BACKGROUND: The accuracy of current tools for predicting adverse events in older inpatients with possible sarcopenia is still insufficient to develop individualized nutrition-related management strategies. The objectives were to develop a machine lea...

Personalised screening tool for early detection of sarcopenia in stroke patients: a machine learning-based comparative study.

Aging clinical and experimental research
BACKGROUND: Sarcopenia is a common complication in patients with stroke, adversely affecting recovery and increasing mortality risk. However, no standardised tool exists for its screening in this population. This study aims to identify factors influe...

Development of an artificial intelligence-based application for the diagnosis of sarcopenia: a retrospective cohort study using the health examination dataset.

BMC medical informatics and decision making
BACKGROUND: Medical imaging techniques for diagnosing sarcopenia have been extensively investigated. Studies have proposed using the T-score and patient information as key diagnostic factors. However, these techniques have either been time-consuming ...

Using Deep Learning to Perform Automatic Quantitative Measurement of Masseter and Tongue Muscles in Persons With Dementia: Cross-Sectional Study.

JMIR aging
BACKGROUND: Sarcopenia (loss of muscle mass and strength) increases adverse outcomes risk and contributes to cognitive decline in older adults. Accurate methods to quantify muscle mass and predict adverse outcomes, particularly in older persons with ...

An explainable machine learning-based prediction model for sarcopenia in elderly Chinese people with knee osteoarthritis.

Aging clinical and experimental research
BACKGROUND: Sarcopenia is an age-related progressive skeletal muscle disease that leads to loss of muscle mass and function, resulting in adverse health outcomes such as falls, functional decline, and death. Knee osteoarthritis (KOA) is a common chro...

Development and multi-center cross-setting validation of an explainable prediction model for sarcopenic obesity: a machine learning approach based on readily available clinical features.

Aging clinical and experimental research
OBJECTIVES: Sarcopenic obesity (SO), characterized by the coexistence of obesity and sarcopenia, is an increasingly prevalent condition in aging populations, associated with numerous adverse health outcomes. We aimed to identify and validate an expla...