AIMC Topic: SARS-CoV-2

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Sharing reliable information worldwide: healthcare strategies based on artificial intelligence need external validation. Position paper.

BMC medical informatics and decision making
Training machine learning models using data from severe COVID-19 patients admitted to a central hospital, where entire wards are specifically dedicated to COVID-19, may yield predictions that differ significantly from those generated using data colle...

The external validity of machine learning-based prediction scores from hematological parameters of COVID-19: A study using hospital records from Brazil, Italy, and Western Europe.

PloS one
The unprecedented worldwide pandemic caused by COVID-19 has motivated several research groups to develop machine-learning based approaches that aim to automate the diagnosis or screening of COVID-19, in large-scale. The gold standard for COVID-19 det...

Rational design and synthesis of pyrazole derivatives as potential SARS-CoV-2 M inhibitors: An integrated approach merging combinatorial chemistry, molecular docking, and deep learning.

Bioorganic & medicinal chemistry
The global impact of SARS-CoV-2 has highlighted the urgent need for novel antiviral therapies. This study integrates combinatorial chemistry, molecular docking, and deep learning to design, evaluate and synthesize new pyrazole derivatives as potentia...

Leveraging deep-learning and unconventional data for real-time surveillance, forecasting, and early warning of respiratory pathogens outbreak.

Artificial intelligence in medicine
BACKGROUND: Controlling re-emerging outbreaks such as COVID-19 is a critical concern to global health. Disease forecasting solutions are extremely beneficial to public health emergency management. This work aims to design and deploy a framework for r...

Using natural language processing to identify patterns associated with depression, anxiety, and stress symptoms during the COVID-19 pandemic.

Journal of affective disorders
BACKGROUND: Combining data-driven natural language processing techniques with traditional methods using predefined word lists may offer greater insights into the connections between language patterns and depression and anxiety symptoms, particularly ...

Pathogen genomic surveillance and the AI revolution.

Journal of virology
The unprecedented sequencing efforts during the COVID-19 pandemic paved the way for genomic surveillance to become a powerful tool for monitoring the evolution of circulating viruses. Herein, we discuss how a state-of-the-art artificial intelligence ...

Artificial-Intelligence Bio-Inspired Peptide for Salivary Detection of SARS-CoV-2 in Electrochemical Biosensor Integrated with Machine Learning Algorithms.

Biosensors
Developing affordable, rapid, and accurate biosensors is essential for SARS-CoV-2 surveillance and early detection. We created a bio-inspired peptide, using the SAGAPEP AI platform, for COVID-19 salivary diagnostics via a portable electrochemical dev...

Identification of patient demographic, clinical, and SARS-CoV-2 genomic factors associated with severe COVID-19 using supervised machine learning: a retrospective multicenter study.

BMC infectious diseases
BACKGROUND: Drivers of COVID-19 severity are multifactorial and include multidimensional and potentially interacting factors encompassing viral determinants and host-related factors (i.e., demographics, pre-existing conditions and/or genetics), thus ...

Comparative Analysis of Machine Learning Algorithms Used for Translating Aptamer-Antigen Binding Kinetic Profiles to Diagnostic Decisions.

ACS sensors
Current approaches for classifying biosensor data in diagnostics rely on fixed decision thresholds based on receiver operating characteristic (ROC) curves, which can be limited in accuracy for complex and variable signals. To address these limitation...

Classification of CT scan and X-ray dataset based on deep learning and particle swarm optimization.

PloS one
In 2019, the novel coronavirus swept the world, exposing the monitoring and early warning problems of the medical system. Computer-aided diagnosis models based on deep learning have good universality and can well alleviate these problems. However, tr...