Skorobogatov et al. developed supervised machine learning models to predict diagnoses and illness states in schizophrenia and bipolar disorder. However, their reliance on bootstrap forests and generalized regressions introduces significant biases in ...
OBJECTIVE: Facial images have been shown to convey mental conditions as clinical symptoms. This study aimed to use facial images to detect patients with drug-naive schizophrenia (DN-SCZ) or chronic schizophrenia (C-SCZ) from healthy controls (HCs), a...
BACKGROUND: Assessing the complex and multifaceted symptoms of patients with acute psychiatric disorders proves to be significantly challenging for clinicians. Moreover, the staff in acute psychiatric wards face high work intensity and risk of burnou...
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Nov 6, 2024
Brain alterations associated with illness severity in schizophrenia remain poorly understood. Establishing linkages between imaging biomarkers and symptom expression may enhance mechanistic understanding of acute psychotic illness. Constructing model...
IEEE journal of biomedical and health informatics
Nov 6, 2024
Schizophrenia (SCZ) is a multifactorial mental illness, thus it will be beneficial for exploring this disease using multimodal data, including functional magnetic resonance imaging (fMRI), genes, and the gut microbiome. Previous studies reported comb...
Journal of magnetic resonance imaging : JMRI
Oct 28, 2024
BACKGROUND: A recent neurodevelopmental rat model, utilizing lactational exposure to polyriboinosinic-polyribocytidilic acid (Poly I:C) leads to mimics of behavioral phenotypes resembling schizophrenia-like symptoms in male offspring and depression-l...
INTRODUCTION: Schizophrenia is a complex mental disorder whose pathophysiology remains elusive, particularly in the roles of subcortex. This study aims to explore the role of subcortex and insula and their relationship with symptom changes in first-e...
Journal of imaging informatics in medicine
Sep 26, 2024
With the increasing prevalence of mental illness, accurate clinical diagnosis of mental illness is crucial. Compared with MRI, CT has the advantages of wide application, low price, short scanning time, and high patient cooperation. This study aims to...
Psychiatry and clinical neurosciences
Sep 18, 2024
BACKGROUND: Recent advances in multivariate pattern recognition have fostered the search for reliable neuroimaging-based biomarkers in psychiatric conditions, including schizophrenia. These approaches consider the complex pattern of alterations in br...
Computer methods and programs in biomedicine
Sep 11, 2024
BACKGROUND AND OBJECTIVE: The accurate diagnosis of schizophrenia spectrum disorder plays an important role in improving patient outcomes, enabling timely interventions, and optimizing treatment plans. Functional connectivity analysis, utilizing func...
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