Bioinformatics (Oxford, England)
Mar 4, 2022
MOTIVATION: In proteomics, database search programs are routinely used for peptide identification from tandem mass spectrometry data. However, many low-quality spectra cannot be interpreted by any programs. Meanwhile, certain high-quality spectra may...
L' Orthodontie francaise
Mar 1, 2022
INTRODUCTION: Manual, tedious cephalometric analyzes of a lack of productivity (errors in plotting and measurement) making the prospect of a fully automated algorithm turning out attractive. The objectives of the study were to evaluate the positionin...
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences
Feb 18, 2022
OBJECTIVE: To establish a deep learning algorithm that can accurately determine three-dimensional facial anatomical landmarks, multi-view stacked hourglass convolutional neural networks (MSH-CNN) and to construct three-dimensional facial midsagittal ...
Mathematical biosciences and engineering : MBE
Feb 9, 2022
Source code is the heart of the software systems; it holds a wealth of knowledge that can be tapped for intelligent software systems and leverage the possibilities of reuse of the software. In this work, exploration revolves around making use of the ...
Bioinformatics (Oxford, England)
Feb 7, 2022
MOTIVATION: Viruses, the most abundant biological entities on earth, are important components of microbial communities, and as major human pathogens, they are responsible for human mortality and morbidity. The identification of viral sequences from m...
Bioinformatics (Oxford, England)
Feb 7, 2022
MOTIVATION: Algorithms for classifying chromosomes, like convolutional deep neural networks (CNNs), show promise to augment cytogeneticists' workflows; however, a critical limitation is their inability to accurately classify various structural chromo...
Bioinformatics (Oxford, England)
Feb 7, 2022
MOTIVATION: Clustering spatial-resolved gene expression is an essential analysis to reveal gene activities in the underlying morphological context by their functional roles. However, conventional clustering analysis does not consider gene expression ...
Bioinformatics (Oxford, England)
Feb 7, 2022
MOTIVATION: DNA methylation plays a key role in a variety of biological processes. Recently, Nanopore long-read sequencing has enabled direct detection of these modifications. As a consequence, a range of computational methods have been developed to ...
Bioinformatics (Oxford, England)
Jan 27, 2022
MOTIVATION: In recent years, cyclic peptide drugs have been receiving increasing attention because they can target proteins that are difficult to be tackled by conventional small-molecule drugs or antibody drugs. Plasma protein binding rate (%PPB) is...
Bioinformatics (Oxford, England)
Jan 27, 2022
MOTIVATION: Teratogenic drugs can cause severe fetal malformation and therefore have critical impact on the health of the fetus, yet the teratogenic risks are unknown for most approved drugs. This article proposes an explainable machine learning mode...