The fusion index is a key indicator for quantifying the differentiation of a myoblast population, which is often calculated manually. In addition to being time-consuming, manual quantification is also error prone and subjective. Several software tool...
AlphaFold2 is an Artificial Intelligence-based program developed to predict the 3D structure of proteins given only their amino acid sequence at atomic resolution. Due to the accuracy and efficiency at which AlphaFold2 can generate 3D structure predi...
Journal of computational biology : a journal of computational molecular cell biology
Jun 26, 2024
Noncoding RNA (NcRNA)-protein interactions (NPIs) play fundamentally important roles in carrying out cellular activities. Although various predictors based on molecular features and graphs have been published to boost the identification of NPIs, most...
Journal of chemical information and modeling
Jun 26, 2024
Artificial intelligence (AI)-aided drug design has demonstrated unprecedented effects on modern drug discovery, but there is still an urgent need for user-friendly interfaces that bridge the gap between these sophisticated tools and scientists, parti...
Anticancer peptides (ACPs), naturally occurring molecules with remarkable potential to target and kill cancer cells. However, identifying ACPs based solely from their primary amino acid sequences remains a major hurdle in immunoinformatics. In the pa...
Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
Jun 24, 2024
Surgeons have dealt with the negative effects of misinformation from "Dr. Google" since patients started using search engines to seek out medical information. With the advent of natural language processing software such as Chat Generative Pre-Trained...
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics
Jun 21, 2024
INTRODUCTION: The accuracy of tooth segmentation in intraoral scans is crucial for performing virtual setups and appliance fabrication. Hence, the objective of this study was to estimate and compare the accuracy of automated tooth segmentation genera...
Classical scoring functions may exhibit low accuracy in determining ligand binding affinity for proteins. The availability of both protein-ligand structures and affinity data make it possible to develop machine-learning models focused on specific pro...
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Jun 20, 2024
The rapid rise of antibiotic resistance and slow discovery of new antibiotics have threatened global health. While novel phage lysins have emerged as potential antibacterial agents, experimental screening methods for novel lysins pose significant cha...
Annual review of biomedical engineering
Jun 20, 2024
Assistive technologies (AT) enable people with disabilities to perform activities of daily living more independently, have greater access to community and healthcare services, and be more productive performing educational and/or employment tasks. Int...
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