AIMC Topic: Squamous Intraepithelial Lesions of the Cervix

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Molecular detection of hrHPV-induced high-grade squamous intraepithelial lesions of the cervix through a targeted RNA next generation sequencing assay.

Molecular medicine (Cambridge, Mass.) May 30, 2025
BACKGROUND: Cervical cancer screening programs are increasingly relying on sensitive molecular approaches as primary tests to detect high-risk human papillomaviruses (hrHPV), the causative agents of cervix cancer. Although hrHPV infection is a pre-re...
Humans Female Adult Uterine Cervical Neoplasms Middle Aged Papillomavirus Infections Early Detection of Cancer Neoplasm Grading RNA, Viral High-Throughput Nucleotide Sequencing Papillomaviridae Squamous Intraepithelial Lesions Squamous Intraepithelial Lesions of the Cervix
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Development of a machine learning-based model for predicting positive margins in high-grade squamous intraepithelial lesion (HSIL) treatment by Cold Knife Conization(CKC): a single-center retrospective study.

BMC women's health Jun 7, 2024
OBJECTIVES: This study aims to analyze factors associated with positive surgical margins following cold knife conization (CKC) in patients with cervical high-grade squamous intraepithelial lesion (HSIL) and to develop a machine-learning-based risk pr...
Humans Machine Learning Retrospective Studies Female Risk Factors Aged Young Adult Adult Uterine Cervical Neoplasms Middle Aged Papillomavirus Infections Logistic Models Margins of Excision Uterine Cervical Dysplasia Cryosurgery Squamous Intraepithelial Lesions Conization Squamous Intraepithelial Lesions of the Cervix
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