AIMC Topic: Margins of Excision

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FACT: foundation model for assessing cancer tissue margins with mass spectrometry.

International journal of computer assisted radiology and surgery
PURPOSE: Accurately classifying tissue margins during cancer surgeries is crucial for ensuring complete tumor removal. Rapid Evaporative Ionization Mass Spectrometry (REIMS), a tool for real-time intraoperative margin assessment, generates spectra th...

Multiparametric MRI and transfer learning for predicting positive margins in breast-conserving surgery: a multi-center study.

International journal of surgery (London, England)
This study aimed to predict positive surgical margins in breast-conserving surgery (BCS) using multiparametric MRI (mpMRI) and radiomics. A retrospective analysis was conducted on data from 444 BCS patients from three Chinese hospitals between 2019 a...

Enhancing surgical precision in squamous cell carcinoma of the head and neck: Hyperspectral imaging and artificial intelligence for improved margin assessment in an ex vivo setting.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
BACKGROUND: Head and neck cancers, constituting 3-5% of all cancer cases, often require surgical resection for optimal outcomes. Achieving complete resection (R0) is crucial, but current methods, relying on white light endoscopy and microscopy, have ...

Untargeted Swab Touch Spray-Mass Spectrometry Analysis with Machine Learning for On-Site Breast Surgical Margin Assessment.

Analytical chemistry
Direct sampling mass spectrometry (MS) has rapidly advanced with the development of ambient ionization MS techniques. Swab touch-spray (TS)-MS has shown promise for rapid clinical diagnostics. However, commercially available swabs are notorious for t...

Stimulated Raman Histology and Artificial Intelligence Provide Near Real-Time Interpretation of Radical Prostatectomy Surgical Margins.

The Journal of urology
PURPOSE: Balancing surgical margins and functional outcomes is crucial during radical prostatectomy for prostate cancer. Stimulated Raman histology (SRH) is a novel, real-time imaging technique that provides histologic images of fresh, unprocessed, a...

A systematic scoping review exploring variation in practice in specimen mammography for Intraoperative Margin Analysis in Breast Conserving Surgery and the role of artificial intelligence in optimising diagnostic accuracy.

European journal of radiology
PURPOSE: Specimen Mammography (SM) is commonly used in Breast Conserving Surgery (BCS) for intraoperative margin analysis. A systematic scoping review was conducted to identify sources of methodological variation in Specimen Mammography Interpretatio...

Deep learning-enabled fluorescence imaging for surgical guidance: training for oral cancer depth quantification.

Journal of biomedical optics
SIGNIFICANCE: Oral cancer surgery requires accurate margin delineation to balance complete resection with post-operative functionality. Current fluorescence imaging systems provide two-dimensional margin assessment yet fail to quantify tumor depth p...

Utilizing deep learning model for assessing melanocytic density in resection margins of lentigo maligna.

Diagnostic pathology
BACKGROUND: Surgical excision with clear histopathological margins is the preferred treatment to prevent progression of lentigo maligna (LM) to invasive melanoma. However, the assessment of resection margins on sun-damaged skin is challenging. We dev...

Artificial Intelligence for Mohs and Dermatologic Surgery: A Systematic Review and Meta-Analysis.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
BACKGROUND: Over the past decade, several studies have shown that potential of artificial intelligence (AI) in dermatology. However, there has yet to be a systematic review evaluating the usage of AI specifically within the field of Mohs micrographic...