Portal hypertension (PHT) is a key event in the evolution of different chronic liver diseases and leads to the morbidity and mortality of patients. The traditional reliable PHT evaluation method is a hepatic venous pressure gradient (HVPG) measuremen...
Biochemical and biophysical research communications
Oct 7, 2017
Here we report the development of a machine-learning model to predict binding affinity based on the crystallographic structures of protein-ligand complexes. We used an ensemble of crystallographic structures (resolution better than 1.5 Å resolution) ...
In clinical practice, an informative and practically useful treatment rule should be simple and transparent. However, because simple rules are likely to be far from optimal, effective methods to construct such rules must guarantee performance, in ter...
Information extraction and knowledge discovery regarding adverse drug reaction (ADR) from large-scale clinical texts are very useful and needy processes. Two major difficulties of this task are the lack of domain experts for labeling examples and int...
Neural networks : the official journal of the International Neural Network Society
Sep 12, 2017
Supervised learning algorithms in a spiking neural network either learn a spike-train pattern for a single neuron receiving input spike-train from multiple input synapses or learn to output the first spike time in a feedforward network setting. In th...
International journal of neural systems
Sep 11, 2017
Changing the metric on the data may change the data distribution, hence a good distance metric can promote the performance of learning algorithm. In this paper, we address the semi-supervised distance metric learning (ML) problem to obtain the best n...
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Sep 1, 2017
Recognition of epileptic seizures from offline EEG signals is very important in clinical diagnosis of epilepsy. Compared with manual labeling of EEG signals by doctors, machine learning approaches can be faster and more consistent. However, the class...
Protein-protein interaction site (PPIS) prediction must deal with the diversity of interaction sites that limits their prediction accuracy. Use of proteins with unknown or unidentified interactions can also lead to missing interfaces. Such data error...
IEEE transactions on pattern analysis and machine intelligence
Aug 22, 2017
We address the problem of video classification for facial analysis and human action recognition. We propose a novel weakly supervised learning method that models the video as a sequence of automatically mined, discriminative sub-events (e.g., onset a...
IEEE transactions on pattern analysis and machine intelligence
Aug 11, 2017
We propose a deep convolutional neural network (CNN) for face detection leveraging on facial attributes based supervision. We observe a phenomenon that part detectors emerge within CNN trained to classify attributes from uncropped face images, withou...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.