BACKGROUND: Microarray datasets are an important medical diagnostic tool as they represent the states of a cell at the molecular level. Available microarray datasets for classifying cancer types generally have a fairly small sample size compared to t...
A novel CAD scheme for automated lung nodule detection is proposed to assist radiologists with the detection of lung cancer on CT scans. The proposed scheme is composed of four major steps: (1) lung volume segmentation, (2) nodule candidate extractio...
Codebook-based feature encodings are a standard framework for image recognition issues. A codebook is usually constructed by clusterings, such as the k-means and the Gaussian Mixture Model (GMM). A codebook size is an important factor to decide the t...
Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews
Jan 10, 2019
In silico toxicity prediction plays an important role in the regulatory decision making and selection of leads in drug design as in vitro/vivo methods are often limited by ethics, time, budget, and other resources. Many computational methods have bee...
Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews
Jan 10, 2019
We introduce here ML4Tox, a framework offering Deep Learning and Support Vector Machine models to predict agonist, antagonist, and binding activities of chemical compounds, in this case for the estrogen receptor ligand-binding domain. The ML4Tox mode...
Arterial spin labeling (ASL) magnetic resonance imaging has been widely applied to identify cerebral blood flow (CBF) abnormalities in a number of brain disorders. To evaluate its significance in detecting methamphetamine (MA) dependence, this study ...
Performing quality control to detect image artifacts and data-processing errors is crucial in structural magnetic resonance imaging, especially in developmental studies. Currently, many studies rely on visual inspection by trained raters for quality ...
Environmental science and pollution research international
Jan 8, 2019
The use of pesticides has been increasing in agriculture, leading to a public health problem. The aim of this study was to evaluate ototoxic effects in farmers who were exposed to cigarette smoke and/or pesticides and to identify possible classificat...
Sleep Apnea is a sleep disorder which causes stop in breathing for a short duration of time that happens to human beings and animals during sleep. Electroencephalogram (EEG) plays a vital role in detecting the sleep apnea by sensing and recording the...
Rapid, accurate prediction of protein structure from amino acid sequence would accelerate fields as diverse as drug discovery, synthetic biology and disease diagnosis. Massively improved prediction of protein structures has been driven by improving t...
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