AIMC Topic: Surface Properties

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A new perspective on antimicrobial therapeutic drug monitoring: Surface-enhanced Raman spectroscopy.

Talanta
Therapeutic drug monitoring (TDM) enables the personalization of treatment regimens, enhancing efficacy in combating infectious diseases while minimizing toxicity risks and reducing the potential for pathogenic resistance. However, existing TDM techn...

A liquid metal-based sticky conductor for wearable and real-time electromyogram monitoring with machine learning classification.

Journal of materials chemistry. B
Skin electronics face challenges related to the interface between rigid and soft materials, resulting in discomfort and signal inaccuracies. This study presents the development and characterization of a liquid metal-polydimethylsiloxane (LM-PDMS) sti...

Surface-Induced Unfolding Reveals Unique Structural Features and Enhances Machine Learning Classification Models.

Analytical chemistry
Native ion mobility-mass spectrometry combined with collision-induced unfolding (CIU) is a powerful analytical method for protein characterization, offering insights into structural stability and enabling the differentiation of analytes with similar ...

Machine Learning for Quantitative Prediction of Protein Adsorption on Well-Defined Polymer Brush Surfaces with Diverse Chemical Properties.

Langmuir : the ACS journal of surfaces and colloids
Polymer informatics has attracted increasing attention because machine learning can establish quantitative structure-property relationships in polymer materials. Understanding and controlling protein adsorption on polymer surfaces are crucial for var...

Liquid-bodied antibiofilm robot with switchable viscoelastic response for biofilm eradication on complex surface topographies.

Science advances
Recalcitrant biofilm infections pose a great challenge to human health. Micro- and nanorobots have been used to eliminate biofilm infections in hard-to-reach regions inside the body. However, applying antibiofilm robots under physiological conditions...

Integrated learning framework for enhanced specific surface area, pore size, and pore volume prediction of biochar.

Bioresource technology
Specific surface area, pore size, and pore volume are essential biochar properties. Optimization typically reduces yield by focusing on per gram of biochar. This work introduces new indicators and an integrated model to balance quality and quantity, ...

Compact Assessment of Molecular Surface Complementarities Enhances Neural Network-Aided Prediction of Key Binding Residues.

Journal of chemical information and modeling
Predicting interactions between proteins is fundamental for understanding the mechanisms underlying cellular processes, since protein-protein complexes are crucial in physiological conditions but also in many diseases, for example by seeding aggregat...

Highly Sensitive and Interference-Free Detection of Multiple Drug Molecules in Serum Using Dual-Modified SERS Substrates Combined with AI Algorithm Analysis.

Analytical chemistry
Surface-enhanced Raman spectroscopy (SERS) technology has shown broad potential in drug concentration detection, but its application in blood drug monitoring faces significant challenges. The primary difficulty lies in overcoming the interference cau...

Deep learning assisted prediction of osteogenic capability of orthopedic implant surfaces based on early cell morphology.

Acta biomaterialia
The surface modification of titanium (Ti) and its alloys is crucial for improving their osteogenic capability, as their bio-inert nature limits effective osseointegration despite their prevalent use in orthopedic implants. However, these modification...

Ultrasensitive Detection of Circulating Plasma Cells Using Surface-Enhanced Raman Spectroscopy and Machine Learning for Multiple Myeloma Monitoring.

Analytical chemistry
Multiple myeloma is a hematologic malignancy characterized by the proliferation of abnormal plasma cells in the bone marrow. Despite therapeutic advancements, there remains a critical need for reliable, noninvasive methods to monitor multiple myeloma...