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Molecular Imprinting

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Electrochemical protein recognition based on macromolecular self-assembly of molecularly imprinted polymer: a new strategy to mimic antibody for label-free biosensing.

Journal of materials chemistry. B
A versatile strategy, based on the use of an amphiphilic copolymer as a macromonomer, was developed for the preparation of a fully synthetic MIP (molecularly imprinted polymer) sensor for protein recognition. A UV-crosslinkable copolymer poly(DMA-co-...

Molecularly imprinted polymer based quartz crystal microbalance sensor for the clinical detection of insulin.

Materials science & engineering. C, Materials for biological applications
In this study, quartz crystal microbalance sensors based on molecular imprinting technology were fabricated for real-time detection of insulin in aqueous solution and artificial plasma. This study describes the preparation of insulin imprinted poly(h...

Preparation of a chemiluminescence sensor for multi-detection of benzimidazoles in meat based on molecularly imprinted polymer.

Food chemistry
In this study, a molecularly imprinted polymer capable of recognizing 8 benzimidazoles was first synthesized. The computation simulation showed that the shape and size of used template were the main factors influencing its recognition ability. Then t...

Cholesterol imprinted composite membranes for selective cholesterol recognition from intestinal mimicking solution.

Colloids and surfaces. B, Biointerfaces
Molecularly imprinted polymers which have been extensively investigated as selective adsorbents were constructed using a template molecule during the polymerization to gain template-specific cavities. In this study, we prepared cholesterol imprinted ...

Spectrophotometric determination of fluoxetine by molecularly imprinted polypyrrole and optimization by experimental design, artificial neural network and genetic algorithm.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
A selective method based on molecularly imprinted polymer (MIP) solid-phase extraction (SPE) using UV-Vis spectrophotometry as a detection technique was developed for the determination of fluoxetine (FLU) in pharmaceutical and human serum samples. Th...

Deep learning-assisted smartphone-based molecularly imprinted electrochemiluminescence detection sensing platform: Protable device and visual monitoring furosemide.

Biosensors & bioelectronics
A novel, portable, and smartphone-based molecularly imprinted polymer electrochemiluminescence (MIP-ECL) sensing platform was constructed for sensitive and selective determination of furosemide (FSM). In this platform, MoSe nanoparticles/starch-deriv...

Harnessing Small-Molecule Analyte Detection in Complex Media: Combining Molecularly Imprinted Polymers, Electrolytic Transistors, and Machine Learning.

ACS applied materials & interfaces
Small-molecule analyte detection is key for improving quality of life, particularly in health monitoring through the early detection of diseases. However, detecting specific markers in complex multicomponent media using devices compatible with point-...

Development of surface molecular-imprinted electrochemical sensor for palmitic acid with machine learning assistance.

Talanta
Palmitic acid (PA) is a kind of saturated high fatty acid, which is involved in physiological safety and food quality. A surface molecularly imprinted polymer (MIP) electrochemical sensor was prepared on MXene surface using dopamine (DA) as functiona...

MIP-based electrochemical sensor with machine learning for accurate ZIKV detection in protein- and glucose-rich urine.

Analytical biochemistry
Nowadays, a multitude of biosensors are being developed worldwide. However, a significant challenge arises when these biosensors are tested in real sample environments, as many of them fail to perform as expected. This can lead to ambiguous results a...

Enhancing the Predictive Performance of Molecularly Imprinted Polymer-Based Electrochemical Sensors Using a Stacking Regressor Ensemble of Machine Learning Models.

ACS sensors
The performance of electrochemical sensors is influenced by various factors. To enhance the effectiveness of these sensors, it is crucial to find the right balance among these factors. Researchers and engineers continually explore innovative approach...