AIMC Topic: Trimethoprim, Sulfamethoxazole Drug Combination

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Severe Acute Respiratory Failure Associated With Trimethoprim/Sulfamethoxazole Among Adolescent and Young Adults: An Active Comparator-Restricted Disproportionality Analysis From the FDA Adverse Event Reporting System (FAERS) Database.

The Annals of pharmacotherapy Feb 26, 2025
BACKGROUND: The US Food and Drug Administration (FDA) has raised concerns about a potential link between trimethoprim/sulfamethoxazole (TMP-SMX) and an increased risk of acute respiratory failure/acute respiratory distress syndrome (ARF/ARDS) in heal...
United States Respiratory Distress Syndrome Child Adverse Drug Reaction Reporting Systems Trimethoprim, Sulfamethoxazole Drug Combination Bayes Theorem Female United States Food and Drug Administration Young Adult Male Adolescent Humans Anti-Bacterial Agents Databases, Factual
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Innovative strategies against superbugs: Developing an AI-CDSS for precise Stenotrophomonas maltophilia treatment.

Journal of global antimicrobial resistance Jun 22, 2024
OBJECTIVES: The World Health Organization named Stenotrophomonas maltophilia (SM) a critical multi-drug resistant threat, necessitating rapid diagnostic strategies. Traditional culturing methods require up to 96 h, including 72 h for bacterial growth...
Artificial Intelligence Machine Learning Anti-Bacterial Agents Microbial Sensitivity Tests Humans Gram-Negative Bacterial Infections Levofloxacin Trimethoprim, Sulfamethoxazole Drug Combination Stenotrophomonas maltophilia Decision Support Systems, Clinical Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Drug Resistance, Multiple, Bacterial
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Malaria Parasitemia and Parasite Density in Antiretroviral-Treated HIV-Infected Adults Following Discontinuation of Cotrimoxazole Prophylaxis.

The Journal of infectious diseases Oct 25, 2016
BACKGROUND:  Cotrimoxazole (CTX) discontinuation increases malaria incidence in human immunodeficiency virus (HIV)-infected individuals. Rates, quantity, and timing of parasitemia rebound following CTX remain undefined.
Plasmodium falciparum Malaria Medication Adherence Kenya Trimethoprim, Sulfamethoxazole Drug Combination Parasite Load Parasitemia Antimalarials Polymerase Chain Reaction Male HIV Infections Female Anti-HIV Agents Prevalence Adult Humans
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Genomic and machine learning approaches to predict antimicrobial resistance in .

Microbiology spectrum Aug 5, 2025
UNLABELLED: is a multidrug-resistant pathogen, which poses a major challenge to clinical management due to its increasing resistance to common antibiotics, such as levofloxacin (LEV) and trimethoprim-sulfamethoxazole (SXT), and poor clinical respons...
Whole Genome Sequencing Gram-Negative Bacterial Infections Mutation Trimethoprim, Sulfamethoxazole Drug Combination Stenotrophomonas maltophilia Levofloxacin Genome, Bacterial Microbial Sensitivity Tests Drug Resistance, Multiple, Bacterial Genomics Bacterial Proteins Machine Learning Anti-Bacterial Agents Humans
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