AIMC Topic: Stenotrophomonas maltophilia

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Impact of COVID-19 isolation measures on ICU microbial resistance dynamics: simulation-based statistical modeling analysis.

Antimicrobial resistance and infection control
BACKGROUND: The transmission of antibiotic-resistant bacteria in intensive care units (ICUs) poses a significant challenge to infection control and patient safety. While direct patient-to-patient transmission is well documented, the relative contribu...

Implementing an AI-enhanced clinical decision support system for Stenotrophomonas maltophilia: a survey-based randomized controlled trial of antibiotic precision and impact on survival.

Implementation science : IS
BACKGROUND: The World Health Organization has identified Stenotrophomonas maltophilia (SM) as a high-risk antibiotic-resistant pathogen. Notably, determining the effectiveness of current antibiotics against SM is challenging, leading to improper ther...

Deciphering the Coevolutionary Dynamics of L2 β-Lactamases via Deep Learning.

Journal of chemical information and modeling
L2 β-lactamases, serine-based class A β-lactamases expressed by , play a pivotal role in antimicrobial resistance (AMR). However, limited studies have been conducted on these important enzymes. To understand the coevolutionary dynamics of L2 β-lactam...

Genomic and machine learning approaches to predict antimicrobial resistance in .

Microbiology spectrum
UNLABELLED: is a multidrug-resistant pathogen, which poses a major challenge to clinical management due to its increasing resistance to common antibiotics, such as levofloxacin (LEV) and trimethoprim-sulfamethoxazole (SXT), and poor clinical respons...