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Tyrosinemias

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Integrating Machine Learning and Follow-Up Variables to Improve Early Detection of Hepatocellular Carcinoma in Tyrosinemia Type 1: A Multicenter Study.

International journal of molecular sciences 40332516
Hepatocellular carcinoma (HCC) is a major complication of tyrosinemia type 1 (HT-1), an inborn error of metabolism affecting tyrosine catabolism. The risk of HCC is higher in late diagnoses despite treatment. Alpha-fetoprotein (AFP) is widely used to...
Adolescent Adult Alanine Transaminase Alkaline Phosphatase alpha-Fetoproteins Biomarkers, Tumor Carcinoma, Hepatocellular Child Child, Preschool Early Detection of Cancer Female Follow-Up Studies Humans Infant Infant, Newborn Liver Neoplasms Longitudinal Studies Machine Learning Male Middle Aged Retrospective Studies Tyrosinemias Young Adult
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