AIMC Topic: Unsupervised Machine Learning

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Unsupervised self-organising map classification of Raman spectra from prostate cell lines uncovers substratified prostate cancer disease states.

Scientific reports
Prostate cancer is a disease which poses an interesting clinical question: Should it be treated? Only a small subset of prostate cancers are aggressive and require removal and treatment to prevent metastatic spread. However, conventional diagnostics ...

Unsupervised machine learning analysis to identify patterns of ICU medication use for fluid overload prediction.

Pharmacotherapy
BACKGROUND: Fluid overload (FO) in the intensive care unit (ICU) is common, serious, and may be preventable. Intravenous medications (including administered volume) are a primary cause for FO but are challenging to evaluate as a FO predictor given th...

Tumor detection on bronchoscopic images by unsupervised learning.

Scientific reports
The diagnosis and early identification of intratracheal tumors relies on the experience of the operators and the specialists. Operations by physicians with insufficient experience may lead to misdiagnosis or misjudgment of tumors. To address this iss...

Unsupervised Non-Rigid Histological Image Registration Guided by Keypoint Correspondences Based on Learnable Deep Features With Iterative Training.

IEEE transactions on medical imaging
Histological image registration is a fundamental task in histological image analysis. It is challenging because of substantial appearance differences due to multiple staining. Keypoint correspondences, i.e., matched keypoint pairs, have been introduc...

OTMorph: Unsupervised Multi-Domain Abdominal Medical Image Registration Using Neural Optimal Transport.

IEEE transactions on medical imaging
Deformable image registration is one of the essential processes in analyzing medical images. In particular, when diagnosing abdominal diseases such as hepatic cancer and lymphoma, multi-domain images scanned from different modalities or different ima...

IGU-Aug: Information-Guided Unsupervised Augmentation and Pixel-Wise Contrastive Learning for Medical Image Analysis.

IEEE transactions on medical imaging
Contrastive learning (CL) is a form of self-supervised learning and has been widely used for various tasks. Different from widely studied instance-level contrastive learning, pixel-wise contrastive learning mainly helps with pixel-wise dense predicti...

Orthogonal Mixed-Effects Modeling for High-Dimensional Longitudinal Data: An Unsupervised Learning Approach.

IEEE transactions on medical imaging
The linear mixed-effects model is commonly utilized to interpret longitudinal data, characterizing both the global longitudinal trajectory across all observations and longitudinal trajectories within individuals. However, characterizing these traject...

Unsupervised Domain Adaptation for EM Image Denoising With Invertible Networks.

IEEE transactions on medical imaging
Electron microscopy (EM) image denoising is critical for visualization and subsequent analysis. Despite the remarkable achievements of deep learning-based non-blind denoising methods, their performance drops significantly when domain shifts exist bet...

Ultrasound Report Generation With Cross-Modality Feature Alignment via Unsupervised Guidance.

IEEE transactions on medical imaging
Automatic report generation has arisen as a significant research area in computer-aided diagnosis, aiming to alleviate the burden on clinicians by generating reports automatically based on medical images. In this work, we propose a novel framework fo...

Style mixup enhanced disentanglement learning for unsupervised domain adaptation in medical image segmentation.

Medical image analysis
Unsupervised domain adaptation (UDA) has shown impressive performance by improving the generalizability of the model to tackle the domain shift problem for cross-modality medical segmentation. However, most of the existing UDA approaches depend on hi...