AIMC Topic: Untranslated Regions

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Deep generative models design mRNA sequences with enhanced translational capacity and stability.

Science (New York, N.Y.) Nov 6, 2025
Despite the success of messenger RNA (mRNA) COVID-19 vaccines, extending this modality to more diseases necessitates substantial enhancements. We present GEMORNA, a generative RNA model that uses transformer architectures tailored for mRNA coding seq...
Humans COVID-19 Female SARS-CoV-2 Animals Deep Learning Mice COVID-19 Vaccines Antibodies, Viral RNA, Messenger Erythropoietin Protein Biosynthesis RNA, Circular Untranslated Regions RNA Stability Luciferases, Firefly
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Porcine single nucleotide polymorphisms and their functional effect: an update.

BMC research notes Dec 4, 2018
OBJECTIVE: To aid in the development of a comprehensive list of functional variants in the swine genome, single nucleotide polymorphisms (SNP) were identified from whole genome sequence of 240 pigs. Interim data from 72 animals in this study was publ...
Animals Male Swine Genome-Wide Association Study Polymorphism, Single Nucleotide DNA Semen High-Throughput Nucleotide Sequencing Molecular Sequence Annotation Gene Ontology Genome Tail Untranslated Regions
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