AIMC Topic: Ursodeoxycholic Acid
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Intrahepatic cholestasis of pregnancy.
Nature reviews. Disease primers
Jul 24, 2025
Intrahepatic cholestasis of pregnancy is the most common pregnancy-related liver disease, manifesting typically during the third trimester of pregnancy with pruritus and elevated serum bile acids. This condition is associated with increased fetal mor...
[The role of bile acid measurement in the management of intrahepatic cholestasis of pregnancy].
Orvosi hetilap
May 15, 2022
Introduction: Intrahepatic cholestasis of pregnancy complicates 1% of pregnancies. It increases the risk of severe fetal complications significantly, including preterm delivery and stillbirth. Objective: To summarize our experience with serum total b...
Prognostic models in primary biliary cholangitis.
Journal of autoimmunity
Nov 9, 2018
Risk prediction modelling is important to better understand the determinants of the course and outcome of PBC and to inform the risk across the disease continuum in PBC enabling risk-stratified follow-up care and personalised therapy. Current prognos...
Validated Spectrophotometric and RP-HPLC-DAD Methods for the Determination of Ursodeoxycholic Acid Based on Derivatization with 2-Nitrophenylhydrazine.
Journal of AOAC International
Dec 23, 2016
This work describes the development, validation, and application of two simple, accurate, and reliable methods for the determination of ursodeoxycholic acid (UDCA) in bulk powder and in pharmaceutical dosage forms. The carboxylic acid group in UDCA w...
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