AIMC Topic: Liver Cirrhosis, Biliary

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Machine learning-based characterization of the gut microbiome associated with the progression of primary biliary cholangitis to cirrhosis.

Microbes and infection May 24, 2024
BACKGROUND: Primary biliary cholangitis (PBC) is associated closely with the gut microbiota. This study aimed to explore the characteristics of the gut microbiota after the progress of PBC to cirrhosis.
Humans Machine Learning Biomarkers Female Aged Adult Male Middle Aged Disease Progression Feces Bacteria Liver Cirrhosis Gastrointestinal Microbiome RNA, Ribosomal, 16S Faecalibacterium Streptococcus Liver Cirrhosis, Biliary Veillonella
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SVM-RFE: selection and visualization of the most relevant features through non-linear kernels.

BMC bioinformatics Nov 19, 2018
BACKGROUND: Support vector machines (SVM) are a powerful tool to analyze data with a number of predictors approximately equal or larger than the number of observations. However, originally, application of SVM to analyze biomedical data was limited be...
Humans Algorithms Survival Rate Biomarkers, Tumor Lymphoma, Large B-Cell, Diffuse Lung Neoplasms Support Vector Machine Computer Graphics Liver Cirrhosis, Biliary
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Prognostic models in primary biliary cholangitis.

Journal of autoimmunity Nov 9, 2018
Risk prediction modelling is important to better understand the determinants of the course and outcome of PBC and to inform the risk across the disease continuum in PBC enabling risk-stratified follow-up care and personalised therapy. Current prognos...
Humans Machine Learning Biomarkers Precision Medicine Prognosis Risk Factors Animals Risk Assessment Genomics Treatment Outcome Metabolomics Models, Statistical Whole Genome Sequencing Alkaline Phosphatase Ursodeoxycholic Acid Liver Cirrhosis, Biliary Cholagogues and Choleretics
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