OBJECTIVES: Growing evidence suggests that vaccines targeting respiratory pathogens have non-specific and broader effects. We aimed to investigate the non-specific effects of respiratory vaccines on acute lower respiratory infection (ALRI) hospitalis...
Respiratory ailments constitute various pathological conditions affecting the respiratory system, including the airways, pulmonary tissues, and associated structures. When these conditions are left untreated or inadequately managed, they can result i...
BACKGROUND: Acute viral respiratory infections (AVRIs) rank among the most common causes of hospitalisation worldwide, imposing significant healthcare burdens and driving the development of pharmacological treatments. However, inconsistent outcome re...
BACKGROUND: Viral respiratory infections (VRTIs) caused by influenza (Flu) and COVID-19 pose significant global health challenges. Clinical outcomes are further exacerbated by infections with hospital acquired drug resistant pathogens (DRPs).
The prompt diagnosis of pulmonary infections with unknown etiology in patients in severe condition remains a challenge due to the lack of rapid and effective diagnostic methods. While metatranscriptomic sequencing offers a powerful approach, its clin...
BACKGROUND: Respiratory viral infections pose a substantial disease burden worldwide. Spatiotemporal techniques help identify transmission patterns of these infections, thereby supporting timely control and prevention efforts. We aimed to synthesise ...
As a prevalent clinical condition, it is critical to distinguish between bacterial and viral respiratory tract infections given their pivotal role in guiding appropriate pharmaceutical interventions and preventing antibiotic misuse. Exhaled breath (E...
OBJECTIVE: During respiratory infections, host-pathogen interaction alters metabolism, leading to changes in the composition of expired volatile organic compounds (VOCs) and soluble immunomodulators. This study aims to identify VOC and blood biomarke...
BACKGROUND: In hospitalized patients, inadequate antibiotic dosage leading to bacterial resistance and increased antimicrobial use intensity due to overexposure to antibiotics are common problems. In the present study, we constructed a machine learni...
Computer methods and programs in biomedicine
Jan 27, 2025
BACKGROUND AND OBJECTIVE: Microbiological culture is a standard diagnostic test that takes a long time to identify lower respiratory tract infections (LRTI) in patients with chronic obstructive pulmonary disease (COPD). This study entailed the develo...
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