This paper presents an intelligent computational framework for modeling nonlinear irreversible biochemical reactions (NIBR) using artificial neural networks (ANNs). The biochemical reactions are modeled using an extended Michaelis-Menten kinetic sche... read more
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Aug 4, 2025
Artificial synaptic devices that mimic neuromorphic signal processing hold great promise for bioelectronic interfaces. However, most systems remain limited to physical stimuli or electroactive small molecules, lacking the ability to transduce biologi... read more
BACKGROUND: Acute cholangitis (AC) presents with significant clinical heterogeneity, and existing severity classifications have limited prognostic value in critically ill patients. Subtypes of AC in critically ill patients have not been investigated. read more
This Perspective article explores the transformative role of artificial intelligence (AI) in predicting perioperative hypoxemia through the integration of deep learning (DL) with multimodal clinical data, including lung imaging, pulmonary function te... read more
BACKGROUND: Sphingolipid metabolism (SM) is linked to acute myocardial infarction (AMI), but its role remains unclear. This study explored SM-related genes (SMRGs) in AMI to support clinical diagnosis. read more
Physical and engineering sciences in medicine
Aug 4, 2025
This study investigates how deep learning (DL) can enhance ovarian cancer diagnosis and staging using large imaging datasets. Specifically, we compare six conventional convolutional neural network (CNN) architectures-ResNet, DenseNet, GoogLeNet, U-Ne... read more
This paper presents a novel deep learning approach for the adaptive fusion of multicultural visual elements in cross-cultural visual communication design for interface development. We address the challenge of creating culturally appropriate digital i... read more
BackgroundVarious methods have been reported for improving the water-insoluble drugs in oral administration formulations. Among them, amorphization has been attracting attention and developed as a method for solubilizing API (active pharmaceutical in... read more
Journal of applied animal welfare science : JAAWS
Aug 4, 2025
Accurate monitoring of animal behavior is critical for assessing welfare and informing conservation strategies for vulnerable species like the eastern hoolock gibbon (). To overcome limitations of manual observation and single-frame analysis in capti... read more
Current first-line treatments of paediatric ulcerative colitis (UC) maintain a 6-month remission in only half of the patients. Relapse prediction at diagnosis could enable earlier introduction of immunosuppressants. We collected intestinal biopsies f... read more
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