Conventional multiplex qPCR faces challenges in quantitative multipathogen detection due to limited fluorescent channels, primer interference, and the high cost of probes. This study developed a novel velocity-controlled PCR (VC-PCR) system integrate... read more
OBJECTIVE: This study aimed to identify diagnostic biomarkers for keloid and explore potential therapeutic agents from traditional Chinese medicine (TCM) by integrating network pharmacology approaches. Specifically, we sought to uncover key molecular... read more
Convolutional neural networks (CNNs) are widely recognized for their high precision in image classification. Nevertheless, the lack of transparency in these black-box models raises concerns in sensitive domains such as healthcare, where understanding... read more
PURPOSE: Accurate preoperative assessment of regional lymphatic metastases (LNM) is essential for effective surgical selection of patients with colorectal cancer (CRC). This study aimed to develop a machine learning (ML) model that integrates radiomi... read more
BACKGROUND: The use of artificial intelligence (AI) to analyze health care data has become common in behavioral health sciences. However, the lack of training opportunities for mental health professionals limits clinicians' ability to adopt AI in cli... read more
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Jan 16, 2026
Cervical spondylotic myelopathy (CSM) and parkinsonian syndromes (PS) present similar motor symptoms, often causing misdiagnosis due to current clinical diagnostic limitations. Misdiagnosis can exacerbate patient conditions or result in unnecessary s... read more
IEEE transactions on computational biology and bioinformatics
Jan 16, 2026
Training machine learning models on large datasets, such as those derived from single-cell RNA sequencing (scRNA-seq), poses significant challenges due to high computational and memory demands. Additionally, integrating data from diverse sources intr... read more
Incoherent k-space undersampling and deep learning-based reconstruction methods have shown great success in accelerating MRI. However, the performance of most previous methods will degrade dramatically under high acceleration factors, e.g., 8× or hig... read more
IEEE transactions on pattern analysis and machine intelligence
Jan 16, 2026
3D reconstruction aims to recover the dense 3D structure of a scene. It plays an essential role in various applications such as Augmented/Virtual Reality (AR/VR), autonomous driving and robotics. Leveraging multiple views of a scene captured from dif... read more
IEEE journal of biomedical and health informatics
Jan 16, 2026
Drug combination therapy has exhibited favorable effects in treating cancer patients, with less toxicity and adverse reactions compared to monotherapy. To accelerate the discovery of therapeutic drug combinations, numerous computational methods have ... read more
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