AIMC Topic: TWEAK Receptor

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Potential role of TNFRSF12A in linking glioblastoma and alzheimer's disease via shared tumour suppressor pathways.

Scientific reports Jul 1, 2025
Tumor suppressor genes (TSGs) are critical regulators of cellular homeostasis and are extensively studied in cancer biology. However, their roles in neurodegenerative diseases, particularly Alzheimer's disease (AD), remain poorly understood. Recent e...
Humans Gene Expression Profiling Transcriptome Cell Line, Tumor Gene Expression Regulation, Neoplastic TWEAK Receptor Glioblastoma Alzheimer Disease Wnt Signaling Pathway Genes, Tumor Suppressor
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Prediction of TNFRSF9 expression and molecular pathological features in thyroid cancer using machine learning to construct Pathomics models.

Endocrine May 16, 2024
BACKGROUND: The TNFRSF9 molecule is pivotal in thyroid carcinoma (THCA) development. This study utilizes Pathomics techniques to predict TNFRSF9 expression in THCA tissue and explore its molecular mechanisms.
Humans Machine Learning Prognosis Female Biomarkers, Tumor Male Middle Aged Transcriptome Thyroid Neoplasms Gene Expression Regulation, Neoplastic TWEAK Receptor
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Predicting TNFRSF4 expression and prognosis in head and neck squamous cell carcinoma tissue: a pathological image analysis approach.

Polish journal of pathology : official journal of the Polish Society of Pathologists Jan 1, 2024
Head and neck squamous cell carcinoma (HNSCC) exhibits a poor 5-year survival rate. TNFRSF4 is gaining attention in tumor therapy. The objective of this study was to forecast the expression of TNFRSF4 in HNSCC tissue using analysis of pathological im...
Humans Prognosis Female Aged Biomarkers, Tumor Male Middle Aged Squamous Cell Carcinoma of Head and Neck Head and Neck Neoplasms TWEAK Receptor
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