The viral expression and immune status in human cancers and insights into novel biomarkers of immunotherapy.
Journal:
BMC cancer
PMID:
34740324
Abstract
BACKGROUND: Viral infections are prevalent in human cancers and they have great diagnostic and theranostic values in clinical practice. Recently, their potential of shaping the tumor immune microenvironment (TIME) has been related to the immunotherapy of human cancers. However, the landscape of viral expressions and immune status in human cancers remains incompletely understood.
Authors
Keywords
Biomarkers, Tumor
DNA, Viral
Epstein-Barr Virus Infections
Genetic Variation
Genome, Viral
Head and Neck Neoplasms
Herpesvirus 4, Human
High-Throughput Nucleotide Sequencing
Humans
Immunotherapy
Kaplan-Meier Estimate
Leukocytes
Machine Learning
Mutation
Neoplasms
Oncogenic Viruses
Papillomaviridae
Papillomavirus Infections
RNA-Seq
Squamous Cell Carcinoma of Head and Neck
Stomach Neoplasms
Support Vector Machine
Transcriptome
Tumor Microenvironment
Tumor Virus Infections