Oncogenic Viruses

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The viral expression and immune status in human cancers and insights into novel biomarkers of immunotherapy.

BMC cancer Nov 5, 2021
BACKGROUND: Viral infections are prevalent in human cancers and they have great diagnostic and theranostic values in clinical practice. Recently, their potential of shaping the tumor immune microenvironment (TIME) has been related to the immunotherap...
Humans Machine Learning Stomach Neoplasms Tumor Microenvironment Biomarkers, Tumor Neoplasms Transcriptome RNA-Seq Immunotherapy Papillomavirus Infections Squamous Cell Carcinoma of Head and Neck Head and Neck Neoplasms Support Vector Machine DNA, Viral Epstein-Barr Virus Infections Herpesvirus 4, Human Mutation Leukocytes Genetic Variation High-Throughput Nucleotide Sequencing Genome, Viral Tumor Virus Infections Kaplan-Meier Estimate Papillomaviridae Oncogenic Viruses
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DeepVISP: Deep Learning for Virus Site Integration Prediction and Motif Discovery.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) Mar 8, 2021
Approximately 15% of human cancers are estimated to be attributed to viruses. Virus sequences can be integrated into the host genome, leading to genomic instability and carcinogenesis. Here, a new deep convolutional neural network (CNN) model is deve...
Humans Reproducibility of Results Neoplasms Deep Learning Hepatitis B virus Herpesvirus 4, Human Cluster Analysis Genome, Human Genomic Instability Herpesvirus 1, Human Oncogenic Viruses Virus Integration
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