Angewandte Chemie (International ed. in English)
Apr 13, 2023
Machine learning (ML) algorithms are currently emerging as powerful tools in all areas of science. Conventionally, ML is understood as a fundamentally data-driven endeavour. Unfortunately, large well-curated databases are sparse in chemistry. In this...
Angewandte Chemie (International ed. in English)
Mar 9, 2023
Multiplex detection of protein post-translational modifications (PTMs), especially at point-of-care, is of great significance in cancer diagnosis. Herein, we report a machine learning-assisted photonic crystal hydrogel (PCH) sensor for multiplex dete...
Angewandte Chemie (International ed. in English)
Feb 14, 2023
Interest in peptide-based supramolecular materials has grown extensively since the 1980s and the application of computational methods has paralleled this. These methods contribute to the understanding of experimental observations based on interaction...
Angewandte Chemie (International ed. in English)
Feb 6, 2023
Small molecule targeting of RNA has emerged as a new frontier in medicinal chemistry, but compared to the protein targeting literature our understanding of chemical matter that binds to RNA is limited. In this study, we reported Repository Of BInders...
Angewandte Chemie (International ed. in English)
Dec 13, 2022
Bioelectronic sensors that report charge changes of a biomolecule upon target binding enable direct and sensitive analyte detection but remain a major challenge for potentiometric measurement, mainly due to Debye Length limitations and the need for m...
Angewandte Chemie (International ed. in English)
Nov 4, 2022
Computer vision as a subcategory of deep learning tackles complex vision tasks by dealing with data of images. Molecular images with exceptionally high resolution have been achieved thanks to the development of techniques like scanning probe microsco...
Angewandte Chemie (International ed. in English)
Jun 7, 2022
Assessing the outcomes of chemical reactions in a quantitative fashion has been a cornerstone across all synthetic disciplines. Classically approached through empirical optimization, data-driven modelling bears an enormous potential to streamline thi...
Angewandte Chemie (International ed. in English)
Jan 12, 2022
"The greatest scientific advance of the next decade will be the implementation of artificial intelligence in any kind of academic discipline … When I was a kid I wanted to be a rock star …" Find out more about Matthias Schiedel in his Introducing … P...
Angewandte Chemie (International ed. in English)
Dec 23, 2021
Manipulation of cell-cell interactions via cell surface engineering has potential biomedical applications in tissue engineering and cell therapy. However, manipulation of the comprehensive and multiple intercellular interactions remains a challenge a...
Angewandte Chemie (International ed. in English)
Sep 24, 2021
Numerous neurochemicals have been implicated in the modulation of brain function, making them appealing analytes for sensors and diagnostics. However, it is a grand challenge to selectively measure multiple neurochemicals simultaneously in vivo becau...