Clinica chimica acta; international journal of clinical chemistry
Apr 17, 2020
Discovery of new protein biomarker candidates has become a major research goal in the areas of clinical chemistry, analytical chemistry, and biomedicine. These important species constitute the molecular target when it comes to diagnosis, prognosis, a...
Clinica chimica acta; international journal of clinical chemistry
Nov 15, 2018
BACKGROUND: LDL cholesterol (LDL-C) has been mainly estimated using the Friedewald equation, and other equations have recently been developed to complement the Friedewald equation. The present study aims to employ a deep neural network (DNN) to impro...
Clinica chimica acta; international journal of clinical chemistry
Feb 25, 2018
In this study, one hundred serum samples from healthy people and patients with rheumatoid arthritis (RA) were analyzed. Standard immunoassays for detection of 10 different RA markers and analysis of glycan markers on antibodies in 10 different assay ...
Clinica chimica acta; international journal of clinical chemistry
Dec 5, 2016
BACKGROUND: Major depressive (MD) disorder is a serious psychiatric disorder that can result in suicidal behavior if not treated. The MD diagnosis using a standardized instrument instead of a structured interview will be advantageous for treatment an...
Clinica chimica acta; international journal of clinical chemistry
Jul 9, 2015
An alternative bioinformatics approach based on fuzzy theory statistics and linear discriminant analysis is proposed for the interpretation of MALDI MS spectra in peptide profiling. When applied, the methodology enables the establishment of a reprodu...
Clinica chimica acta; international journal of clinical chemistry
Jun 15, 2015
BACKGROUND: Familial hypercholesterolaemia (FH) is the most common monogenic cause of premature atherosclerotic cardiovascular disease (CVD). However, most individuals with FH remain undiagnosed. We sought to determine if an expert system (ES) at a c...
Clinica chimica acta; international journal of clinical chemistry
Jun 15, 2025
The integration of artificial intelligence (AI) into point-of-care testing (POCT) represents a transformative leap in modern healthcare, addressing critical challenges in diagnostic accuracy, workflow efficiency, and equitable access. While POCT has ...