AIMC Topic: Cholesterol, LDL

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Machine learning-based prediction of LDL cholesterol: performance evaluation and validation.

PeerJ Apr 9, 2025
OBJECTIVE: This study aimed to validate and optimize a machine learning algorithm for accurately predicting low-density lipoprotein cholesterol (LDL-C) levels, addressing limitations of traditional formulas, particularly in hypertriglyceridemia.
Female Aged Adult Machine Learning Algorithms Risk Assessment Cholesterol, LDL Triglycerides Male Middle Aged Humans Hypertriglyceridemia
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Can small dense LDL cholesterol be estimated from the lipid profile?

Current opinion in lipidology Apr 3, 2025
PURPOSE OF REVIEW: Small dense low-density lipoprotein cholesterol (sdLDL-C) is recognized for its strong atherosclerogenic potential. However, its direct measurement remains impractical in clinical settings due to its high cost, time constraints, an...
Biomarkers Cardiovascular Diseases Cholesterol, LDL Humans Machine Learning
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Deep learning-based LDL-C level prediction and explainable AI interpretation.

Computers in biology and medicine Feb 26, 2025
This study investigates the use of deep learning (DL) models to predict low-density lipoprotein cholesterol (LDL-C) levels. The dataset obtained from New York-Presbyterian Hospital/Weill Cornell Medical Center includes triglycerides (TG), total chole...
Cholesterol, LDL Female Humans Male Deep Learning
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Predicting low density lipoprotein cholesterol target attainment using machine learning in patients with coronary artery disease receiving moderate-dose statin therapy.

Scientific reports Feb 13, 2025
Low-density lipoprotein cholesterol (LDL-C) is an important factor in the development of cardiovascular disease, making its management a key aspect of cardiovascular health. While high-dose statin therapy is often recommended for LDL-C reduction, car...
Humans Cholesterol, LDL Coronary Artery Disease Hydroxymethylglutaryl-CoA Reductase Inhibitors Machine Learning Male Middle Aged Female Aged
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Comparison between statistical and machine learning methods to detect the hematological indices with the greatest influence on elevated serum levels of low-density lipoprotein cholesterol.

Chemistry and physics of lipids Oct 5, 2024
INTRODUCTION: Elevated levels of low-density lipoprotein-cholesterol (LDL-C) is a significant risk factor for the development of cardiovascular diseases (CVD)s. Furthermore, studies have revealed an association between indices of the complete blood c...
Male Middle Aged Blood Cell Count Cholesterol, LDL Aged Humans Adult Machine Learning Prospective Studies Female
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Explainable artificial intelligence for LDL cholesterol prediction and classification.

Clinical biochemistry Jul 6, 2024
INTRODUCTION: Monitoring LDL-C levels is essential in clinical practice because there is a direct relation between low-density lipoprotein cholesterol (LDL-C) levels and atherosclerotic heart disease risk. Therefore, measurement or estimate of LDL-C ...
Humans Artificial Intelligence Middle Aged Support Vector Machine Cholesterol, LDL Aged Retrospective Studies Adult Female Male
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A comparative evaluation of low-density lipoprotein cholesterol estimation: Machine learning algorithms versus various equations.

Clinica chimica acta; international journal of clinical chemistry Mar 9, 2024
BACKGROUND: Given the critical importance of Low-density lipoprotein cholesterol (LDL-C) levels in determining cardiovascular risk, it is essential to measure LDL-C accurately. Since the Friedewald formula generates incorrect predictions in many circ...
Humans Bayes Theorem Triglycerides Cholesterol, LDL Machine Learning
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TRENDS IN CHOLESTEROL AND LIPOPROTEINS ARE ASSOCIATED WITH ACUTE RESPIRATORY DISTRESS SYNDROME INCIDENCE AND DEATH AMONG SEPSIS PATIENTS.

Shock (Augusta, Ga.) Dec 28, 2023
Objective: Compare changes in cholesterol and lipoprotein levels occurring in septic patients with and without acute respiratory distress syndrome (ARDS) and by survivorship. Methods: We reanalyzed data from prospective sepsis studies. Cholesterol an...
Respiratory Distress Syndrome Lipoproteins Sepsis Cholesterol, LDL Apolipoprotein A-I Incidence Humans Cholesterol Prospective Studies
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Familial hypercholesterolemia diagnostic challenge: Is Artificial Intelligence the key?

Atherosclerosis Dec 27, 2023
Cholesterol, LDL Hyperlipoproteinemia Type II Humans Artificial Intelligence
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Cholesterol Levels, Hormone Replacement Therapy, and Incident Dementia among Older Adult Women.

Nutrients Oct 23, 2023
Previous studies revealed that hormone replacement therapy (HRT) probably has a protective effect for preventing dementia in post-menopausal women. However, the results were still controversial. The association between cholesterol levels and incident...
Humans Female Aged Hormone Replacement Therapy Artificial Intelligence Cholesterol, LDL Retrospective Studies Alzheimer Disease
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