AIMC Topic: Cholesterol, LDL

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Machine learning-based prediction of LDL cholesterol: performance evaluation and validation.

PeerJ Apr 9, 2025
OBJECTIVE: This study aimed to validate and optimize a machine learning algorithm for accurately predicting low-density lipoprotein cholesterol (LDL-C) levels, addressing limitations of traditional formulas, particularly in hypertriglyceridemia.
Humans Female Aged Adult Machine Learning Algorithms Hypertriglyceridemia Risk Assessment Cholesterol, LDL Triglycerides Male Middle Aged
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Deep learning-based LDL-C level prediction and explainable AI interpretation.

Computers in biology and medicine Feb 26, 2025
This study investigates the use of deep learning (DL) models to predict low-density lipoprotein cholesterol (LDL-C) levels. The dataset obtained from New York-Presbyterian Hospital/Weill Cornell Medical Center includes triglycerides (TG), total chole...
Humans Cholesterol, LDL Male Deep Learning Female
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Predicting low density lipoprotein cholesterol target attainment using machine learning in patients with coronary artery disease receiving moderate-dose statin therapy.

Scientific reports Feb 13, 2025
Low-density lipoprotein cholesterol (LDL-C) is an important factor in the development of cardiovascular disease, making its management a key aspect of cardiovascular health. While high-dose statin therapy is often recommended for LDL-C reduction, car...
Machine Learning Female Cholesterol, LDL Aged Male Humans Coronary Artery Disease Middle Aged Hydroxymethylglutaryl-CoA Reductase Inhibitors
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Comparison between statistical and machine learning methods to detect the hematological indices with the greatest influence on elevated serum levels of low-density lipoprotein cholesterol.

Chemistry and physics of lipids Oct 5, 2024
INTRODUCTION: Elevated levels of low-density lipoprotein-cholesterol (LDL-C) is a significant risk factor for the development of cardiovascular diseases (CVD)s. Furthermore, studies have revealed an association between indices of the complete blood c...
Cholesterol, LDL Blood Cell Count Male Middle Aged Machine Learning Prospective Studies Aged Adult Female Humans
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Explainable artificial intelligence for LDL cholesterol prediction and classification.

Clinical biochemistry Jul 6, 2024
INTRODUCTION: Monitoring LDL-C levels is essential in clinical practice because there is a direct relation between low-density lipoprotein cholesterol (LDL-C) levels and atherosclerotic heart disease risk. Therefore, measurement or estimate of LDL-C ...
Cholesterol, LDL Retrospective Studies Middle Aged Support Vector Machine Female Humans Adult Artificial Intelligence Male Aged
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A comparative evaluation of low-density lipoprotein cholesterol estimation: Machine learning algorithms versus various equations.

Clinica chimica acta; international journal of clinical chemistry Mar 9, 2024
BACKGROUND: Given the critical importance of Low-density lipoprotein cholesterol (LDL-C) levels in determining cardiovascular risk, it is essential to measure LDL-C accurately. Since the Friedewald formula generates incorrect predictions in many circ...
Humans Machine Learning Triglycerides Bayes Theorem Cholesterol, LDL
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TRENDS IN CHOLESTEROL AND LIPOPROTEINS ARE ASSOCIATED WITH ACUTE RESPIRATORY DISTRESS SYNDROME INCIDENCE AND DEATH AMONG SEPSIS PATIENTS.

Shock (Augusta, Ga.) Dec 28, 2023
Objective: Compare changes in cholesterol and lipoprotein levels occurring in septic patients with and without acute respiratory distress syndrome (ARDS) and by survivorship. Methods: We reanalyzed data from prospective sepsis studies. Cholesterol an...
Respiratory Distress Syndrome Humans Cholesterol, LDL Lipoproteins Sepsis Prospective Studies Apolipoprotein A-I Cholesterol Incidence
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Familial hypercholesterolemia diagnostic challenge: Is Artificial Intelligence the key?

Atherosclerosis Dec 27, 2023
Cholesterol, LDL Humans Hyperlipoproteinemia Type II Artificial Intelligence
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Cholesterol Levels, Hormone Replacement Therapy, and Incident Dementia among Older Adult Women.

Nutrients Oct 23, 2023
Previous studies revealed that hormone replacement therapy (HRT) probably has a protective effect for preventing dementia in post-menopausal women. However, the results were still controversial. The association between cholesterol levels and incident...
Hormone Replacement Therapy Cholesterol, LDL Alzheimer Disease Female Aged Artificial Intelligence Retrospective Studies Humans
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Dataset dependency of low-density lipoprotein-cholesterol estimation by machine learning.

Annals of clinical biochemistry Jun 5, 2023
OBJECTIVES: We evaluated the applicability of a machine learning-based low-density lipoprotein-cholesterol (LDL-C) estimation method and the influence of the characteristics of the training datasets.
Humans Cholesterol, LDL Machine Learning Triglycerides Research Design
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