The international journal of neuropsychopharmacology
May 10, 2015
BACKGROUND: There are no objective, biological markers that can robustly predict methylphenidate response in attention deficit hyperactivity disorder. This study aimed to examine whether applying machine learning approaches to pretreatment demographi...
The international journal of neuropsychopharmacology
Apr 11, 2025
BACKGROUND: The global prevalence of dementia is significantly increasing. Early detection and prevention strategies, particularly for mild cognitive impairment (MCI), are crucial but currently hindered by the lack of established biomarkers. Here, we...
The international journal of neuropsychopharmacology
Nov 26, 2020
BACKGROUND: There is a lack of reliable biomarkers for major depressive disorder (MDD) in clinical practice. However, several studies have shown an association between alterations in microRNA levels and MDD, albeit none of them has taken advantage of...
The international journal of neuropsychopharmacology
May 27, 2020
In psychiatry we often speak of constructing "models." Here we try to make sense of what such a claim might mean, starting with the most fundamental question: "What is (and isn't) a model?" We then discuss, in a concrete measurable sense, what it mea...