AIMC Topic: A Kinase Anchor Proteins

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TM-Score predicts immunotherapy efficacy and improves the performance of the machine learning prognostic model in gastric cancer.

International immunopharmacology May 8, 2024
Immunotherapy is becoming increasingly important, but the overall response rate is relatively low in the treatment of gastric cancer (GC). The application of tumor mutational burden (TMB) in predicting immunotherapy efficacy in GC patients is limited...
Humans Machine Learning Prognosis Stomach Neoplasms Tumor Microenvironment Biomarkers, Tumor Immunotherapy Treatment Outcome Mutation A Kinase Anchor Proteins
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A 21‑gene Support Vector Machine classifier and a 10‑gene risk score system constructed for patients with gastric cancer.

Molecular medicine reports Nov 21, 2019
Gastric cancer (GC) ranks fifth in terms of incidence and third in terms of tumor mortality worldwide. The present study was designed to construct a Support Vector Machine (SVM) classifier and risk score system for GC. The GSE62254 (training set) and...
Humans Cytokines Prognosis Female Risk Factors Aged Stomach Neoplasms Male Middle Aged Gene Expression Profiling Gene Regulatory Networks Gene Expression Regulation, Neoplastic Membrane Proteins Support Vector Machine Databases, Genetic Carrier Proteins Nerve Tissue Proteins Neoplasm Recurrence, Local Tumor Suppressor Proteins Kaplan-Meier Estimate Angiopoietin-like Proteins A Kinase Anchor Proteins Angiopoietin-Like Protein 1
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