Colorectal cancer (CRC) is one of the most common types of cancer among men and women. The grading of dysplasia and the detection of adenocarcinoma are important clinical tasks in the diagnosis of CRC and shape the patients' follow-up plans. This stu...
A model's ability to express its own predictive uncertainty is an essential attribute for maintaining clinical user confidence as computational biomarkers are deployed into real-world medical settings. In the domain of cancer digital histopathology, ...
BACKGROUND: Solid pulmonary nodules are different from subsolid nodules and the diagnosis is much more challenging. We intended to evaluate the diagnostic and prognostic value of radiomics and deep learning technologies for solid pulmonary nodules.
Acta radiologica (Stockholm, Sweden : 1987)
Oct 31, 2022
BACKGROUND: Deep learning algorithms (DLAs) could enable automatic measurements of solid portions of mixed ground-glass nodules (mGGNs) in agreement with the invasive component sizes measured during pathologic examinations. However, the measurement o...
Computational and mathematical methods in medicine
Oct 27, 2022
METHODS: Patients (363 in total) with stomach adenocarcinoma from The Cancer Genome Atlas (TCGA) cohort were included. An autoencoder was constructed to integrate the RNA sequencing, miRNA sequencing, and methylation data. The features of the bottlen...
International journal of molecular sciences
Sep 29, 2022
Genes are composed of DNA and each gene has a specific sequence. Recombination or replication within the gene base ends in a permanent change in the nucleotide collection in a DNA called mutation and some mutations can lead to cancer. Breast adenocar...
Computer methods and programs in biomedicine
Sep 7, 2022
BACKGROUND: Lung cancer has the highest mortality rate in the world, twice as high as the second highest. On the other hand, pathologists are overworked and this is detrimental to the time spent on each patient, diagnostic turnaround time, and their ...
Computational intelligence and neuroscience
Aug 30, 2022
With an astounding five million fatal cases every year, lung cancer is among the leading causes of mortality worldwide for both men and women. The diagnosis of lung illnesses can benefit from the information a computed tomography (CT) scan can offer....
PURPOSE: To develop a novel multimodal data fusion model by incorporating computed tomography (CT) images and clinical variables based on deep learning for predicting the invasiveness risk of stage I lung adenocarcinoma that manifests as ground-glass...
International journal of surgical pathology
Jul 27, 2022
The diversifying modalities of treatment for gastric cancer raise urgent demands for the rapid and precise diagnosis of metastases in regional lymph nodes, thereby significantly impact the workload of pathologists. Meanwhile, the recent advent of wh...