Aging is a natural phenomenon characterized by the loss of normal morphology and physiological functioning of the body, causing wrinkles on the skin, loss of hair, and compromised immune systems. Peptide therapies have emerged as a promising approach...
Deep learning for microbiome analysis has shown potential for understanding microbial communities and human phenotypes. Here, we propose an approach, Transformer-based Robust Principal Component Analysis(TRPCA), which leverages the strengths of trans...
This cross-sectional investigation seeks to examine the association between dietary omega-3 fatty acids (including α-linolenic acid [ALA], eicosapentaenoic acid [EPA], and docosahexaenoic acid [DHA]) and biomarkers of cellular aging, specifically DNA...
Ischemic stroke (IS) affects 11 million people annually, posing substantial clinical and economic burdens. Current therapies remain limited by time sensitivity and variable efficacy, necessitating novel biomarkers. We developed a multi-omics framewor...
Timely detection of cognitive decline is paramount for effective intervention, prompting researchers to leverage EEG pattern analysis, focusing particularly on cognitive load, to establish reliable markers for early detection and intervention. This c...
Social anxiety disorder (SAD) is a prevalent psychiatric condition with significant psychological and socioeconomic consequences. While its psychological characteristics are well-documented, the underlying molecular mechanisms remain poorly understoo...
BACKGROUND: Ageing is a heterogeneous process, which is associated with heterogeneous resilience in older people. Cancer surgery and treatment may be associated with accelerated ageing in some older people; studying this process will improve understa...
Artificial intelligence (AI) is increasingly impacting multiple domains. The application of AI in nutrition and ageing research has significant potential to transform healthcare outcomes for the ageing population. This review provides critical insigh...
BACKGROUND: To investigate the association between the Dietary Inflammatory Index (DII), biological aging, and the staging and mortality of cardiovascular-kidney-metabolic (CKM) syndrome.
Cellular senescence is an irreversible state of cell cycle arrest with a complex role in tissue repair, aging, and disease. However, inconsistencies in identifying cellular senescence have led to varying conclusions about their functional significanc...
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