The detection of patients in the cognitive normal (CN), mild cognitive impairment (MCI), and Alzheimer's disease (AD) stages of neurodegeneration is crucial for early treatment interventions. However, the heterogeneity of MCI data samples poses a cha...
The clinical spectrum of Alzheimer's disease (AD) ranges dynamically from asymptomatic and mild cognitive impairment (MCI) to mild, moderate, or severe AD. Although a few disease-modifying treatments, such as lecanemab and donanemab, have been develo...
Machine learning has gained attention in the medical field. Continuous efforts are being made to develop robust models for early prognosis purposes. The brain is the most pivotal organ in the human body. A brain stroke is generally caused by a blocka...
BACKGROUND: Although digital technology represents a growing field aiming to revolutionize early Alzheimer disease risk prediction and monitoring, the perspectives of older adults on an integrated digital brain health platform have not been investiga...
Medical & biological engineering & computing
Nov 15, 2024
Alzheimer's disease (AD) refers to a neurological disorder that causes damage to brain cells and results in decreasing cognitive abilities and memory. In brain scans, this degeneration can be seen in different ways. The disease can be classified into...
BACKGROUND: Recently, there has been a growing interest in combining causal inference with machine learning algorithms. Double machine learning model (DML), as an implementation of this combination, has received widespread attention for their experti...
Accurate and early disease detection is crucial for improving patient care, but traditional diagnostic methods often fail to identify diseases in their early stages, leading to delayed treatment outcomes. Early diagnosis using blood derivatives as a ...
Computer methods and programs in biomedicine
Nov 12, 2024
BACKGROUND AND OBJECTIVES: Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD) are progressive neurological disorders that significantly impair the cognitive functions, memory, and daily activities. They affect millions of individuals worldw...
BACKGROUND: The field of Alzheimer's disease (AD) diagnosis is undergoing significant transformation due to the application of deep learning (DL) models. While DL surpasses traditional machine learning in disease prediction from structural magnetic r...
Journal of the Chinese Medical Association : JCMA
Nov 8, 2024
BACKGROUND: Alzheimer disease is a progressive neurological disorder marked by irreversible memory loss and cognitive decline. Traditional diagnostic tools, such as intracranial volume assessments, electroencephalography (EEG) signals, and brain magn...
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