AIMC Topic: Animals

Clear Filters Showing 261 to 270 of 8866 articles

Advancing Cell Therapy to Enhance Passive Avoidance Memory: Integrative Approaches Combining Neural-Like Cells and Rosmarinic Acid Through Behavioral, Molecular, and Histological Analyses.

Neurochemical research
Alzheimer's disease (AD) is characterized by progressive neurodegeneration, synaptic dysfunction, and cognitive decline. Regenerative strategies aim to replace lost neurons and modulate the inflammatory milieu to restore neural networks. This study e...

Microfluidic-based nanocarriers for overcoming biological barriers in therapeutic delivery systems.

Nanoscale
Microfluidic technologies have revolutionized the synthesis of nanocarriers for drug and gene delivery, providing unparalleled precision and efficiency in the production of therapeutic nanoparticles. This review highlights recent advancements in micr...

Ultrasound-responsive nanocarriers for cancer therapy: Physiochemical features-directed design.

Journal of controlled release : official journal of the Controlled Release Society
The design of ultrasound (US)-responsive nanocarriers (URNs) guided by their physicochemical characteristics represents a pivotal strategy for advancing cancer therapy. By exploiting the intrinsic physicochemical properties of diverse nanocarriers, i...

Nondestructive VOC-Based Phenotyping Strategy for Assessing Brown Planthopper Resistance at the Adult Stage in Rice.

Journal of agricultural and food chemistry
The brown planthopper (BPH) is a major rice pest in Asia, with the most severe damage occurring at the adult stage in rice. Although breeding resistant varieties is key to pest control, current screening focuses mainly on seedlings using destructive,...

Label-free robotic mitochondrial biopsy.

Science advances
Robotic micromanipulation has advanced cellular probing, yet achieving precise, minimally invasive intracellular operations without fluorescent labeling remains challenging. Fluorescent techniques often cause photodamage and cytotoxicity and interfer...

A multistep platform identifies spleen-tropic lipid nanoparticles for in vivo T cell-targeted delivery of gene-editing proteins.

Science advances
Lipid nanoparticles (LNPs) are a promising nonviral delivery system for gene-editing proteins, but optimal formulations remain underexplored. Unlike messenger RNA-based approaches, ribonucleoprotein delivery enables immediate genome editing without r...

Functional motor mapping of domestic pig lumbar spinal cord using penetrating microelectrodes.

Journal of neuroengineering and rehabilitation
The restoration of standing and walking after spinal cord injury (SCI) remains a top priority for individuals with paraplegia. Despite significant advancements in neuromodulation techniques, challenges such as limited selectivity and inconsistent out...

An enhanced blood-sucking leech optimization for training feedforward neural networks.

Scientific reports
The input, hidden and output layers cultivate a hierarchical framework of the feedforward neural networks (FNNs) characterized by unidirectional information flow and feedback feedback-free loop connection, the network highlights attributes of fortifi...

Machine learning predictions of climate change effects on nearly threatened bird species (Crithagra xantholaema) habitat in Ethiopia for conservation strategies.

Scientific reports
Endemic and endangered bird species, such as Salvadori serin (C. xantholaema), are vulnerable to environmental and anthropogenic changes. Understanding the impact of climate change on ecological niches is essential for effective conservation. This st...

Strongly nonlinear age-structured equation, time-elapsed model and large delays.

Journal of mathematical biology
The time-elapsed model for neural assemblies is a nonlinear age-structured equation where the renewal term describes the network activity and influences the discharge rate, possibly with a delay due to the length of connections. We first solve a long...